PIPA517507

TAK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517507-Each-of-1 In Stock ₹ 50,565.96

PIPA517507 - Each of 1

₹ 50,565.96

In Stock

Quantity

1

Base Price: ₹ 50,565.96

GST (18%): ₹ 9,101.873

Total Price: ₹ 59,667.833

Antigen

TAK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K7

Gene Alias

B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26409, 313121, 529146, 6885

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

27 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

A2VDU3, O43318, P0C8E4, Q62073

Gene Symbols

MAP3K7

Immunogen

Synthetic peptide corresponding to residues near the carboxy-terminus of human TAK1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Rat, Rat, X. laevis

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA518523

--

Img

Thermo Scientific

PIPA517480

--

Img

Thermo Scientific

PIPA517677

--

Img

Thermo Scientific

PIPA517889

--

Img

Thermo Scientific

PIPA517689

--

Img

Thermo Scientific

PIPA517729

--

Img

Thermo Scientific

PIPA517574

--

Img

Thermo Scientific

PIPA517606

--

Description

  • It is not recommended to aliquot this antibody
  • TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA517507

--


Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 313121, 529146, 6885

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
27 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
A2VDU3, O43318, P0C8E4, Q62073

Gene Symbols:
MAP3K7

Immunogen:
Synthetic peptide corresponding to residues near the carboxy-terminus of human TAK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Rat, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517510

--


Antigen:
PP2A alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP2CA

Gene Alias:
B55-GAMMA; hypothetical protein; IMYPNO; IMYPNO1; Methyl-PPP2CA; MGC33570; PP2A; PP2A alpha; PP2A C terminal; PP2A L9; PP2A Leucine 9; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; Ppp2ca; PR52; PR55G; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 catalytic subunit alpha; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2,catalytic subunit alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A; protein phosphatase-2A-alpha; R75353; replication protein C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19052, 24672, 5515

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
27 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P63330, P63331, P67775

Gene Symbols:
PPP2CA

Immunogen:
Synthetic peptide corresponding to amino acids at the carboxy terminus of human PP2A catalytic subunit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Drosophila, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517511

--


Antigen:
COX4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COX4I1

Gene Alias:
AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158, member B; FLJ23483; hypothetical protein MGC73355; IV-1; mg:bb02d03; MGC72016; Neighbor of COX4; NOC4; Protein FAM158B; XELAEV_18024950mg; zgc:110058; zgc:73355

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12857, 1327, 281090, 29445

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
194 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P00423, P10888, P13073, P19783

Gene Symbols:
COX4I1

Immunogen:
Synthetic peptide corresponding to residues surrounding Lys29 of human COX IV

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517513

--


Antigen:
Phospho-AMPK beta-1 (Ser182)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKAB1

Gene Alias:
1300015D22Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase, beta subunit; AAKB1; AMP-activated protein kinase beta subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta-1 chain; AMPK subunit beta-1; AMPKb; AMPK-beta1; AU021155; E430008F22; HAMPKb; kinase AMPK-beta1; kinase pAMPK; pAMPK; Prkab1; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19079, 5564, 83803

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P80386, Q9R078, Q9Y478

Gene Symbols:
PRKAB1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer182 of human AMPKβ1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG