PIPA517608
APS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517608-Each-of-1 | In Stock | ₹ 38,844.24 |
PIPA517608 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,844.24
GST (18%): ₹ 6,991.963
Total Price: ₹ 45,836.203
Antigen
APS
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
O14492, Q9JID9
Gene Symbols
SH2B2
Immunogen
Synthetic peptide corresponding to residues near the amino-terminus of human APS
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Gene
SH2B2
Gene Alias
adapter protein with pleckstrin homology and Src homology 2 domains; adaptor protein with pleckstrin homology and src homology 2 domains; Alpha-1-antitrypsin; Aps; SH2 and PH domain-containing adapter protein APS; SH2B adapter protein 2; SH2B adaptor protein 2; Sh2b2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10603, 23921
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other adaptor/docking proteins
- APS (adapter protein with Pleckstrin homology and Src homology 2 domains) a member of the Lnk family, is an adaptor protein that is involved in B-cell signaling, insulin signaling, cytoskeletal reorganization
- It is tyrosine phosphorylated by JAK2, KIT and other kinases during B-cell receptor stimulation of many different cytokines, chemokines and leukokines
- APS has been shown to inhibit the JAK-STAT pathway in collaboration with c-Cbl
- It is located in the cytoplasm in pre-PDGF (platelet derived growth factor) stimulated cells and localizes to the plasma membrane and peripheral regions upon PDGF stimulation
- This protein is expressed in B-cells and mast cells when detected in haematopoietic cell lines yet is also expressed in many different tissues including spleen, prostrate, testis, uterus, small intestine and skeletal muscle.
Compare Similar Items
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Antigen: APS
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O14492, Q9JID9
Gene Symbols: SH2B2
Immunogen: Synthetic peptide corresponding to residues near the amino-terminus of human APS
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Gene: SH2B2
Gene Alias: adapter protein with pleckstrin homology and Src homology 2 domains; adaptor protein with pleckstrin homology and src homology 2 domains; Alpha-1-antitrypsin; Aps; SH2 and PH domain-containing adapter protein APS; SH2B adapter protein 2; SH2B adaptor protein 2; Sh2b2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10603, 23921
Content And Storage: -20°C
Form: Liquid
Antigen:
APS
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
O14492, Q9JID9
Gene Symbols:
SH2B2
Immunogen:
Synthetic peptide corresponding to residues near the amino-terminus of human APS
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Gene:
SH2B2
Gene Alias:
adapter protein with pleckstrin homology and Src homology 2 domains; adaptor protein with pleckstrin homology and src homology 2 domains; Alpha-1-antitrypsin; Aps; SH2 and PH domain-containing adapter protein APS; SH2B adapter protein 2; SH2B adaptor protein 2; Sh2b2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10603, 23921
Content And Storage:
-20°C
Form:
Liquid
Antigen: MXD1
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P50538, Q05195
Gene Symbols: MXD1
Immunogen: Synthetic peptide corresponding to the carboxy terminus region of Mad-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: MXD1
Gene Alias: antagonizer of myc transcriptional activity; AW122478; BHLHC58; Mad; Mad1; Mad-1; max dimerization protein 1; Max dimerizer 1; MAX-binding protein; MGC104659; mxd1; OTTHUMP00000202211; Protein MAD; si:dkey-202n14.4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17119, 362391, 4084
Content And Storage: -20°C
Form: Liquid
Antigen:
MXD1
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P50538, Q05195
Gene Symbols:
MXD1
Immunogen:
Synthetic peptide corresponding to the carboxy terminus region of Mad-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
MXD1
Gene Alias:
antagonizer of myc transcriptional activity; AW122478; BHLHC58; Mad; Mad1; Mad-1; max dimerization protein 1; Max dimerizer 1; MAX-binding protein; MGC104659; mxd1; OTTHUMP00000202211; Protein MAD; si:dkey-202n14.4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17119, 362391, 4084
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-eIF4B (Ser422)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P23588, Q8BGD9
Gene Symbols: Eif4b
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer422 of human eIF4B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Eif4b
Gene Alias: 2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1975, 300253, 75705
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-eIF4B (Ser422)
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P23588, Q8BGD9
Gene Symbols:
Eif4b
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer422 of human eIF4B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Eif4b
Gene Alias:
2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1975, 300253, 75705
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-IKK gamma (Ser376)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: Q9Y6K9
Gene Symbols: Ikbkg
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human IKK gamma protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Ikbkg
Gene Alias: 1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKBKG; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8517
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IKK gamma (Ser376)
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
Q9Y6K9
Gene Symbols:
Ikbkg
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human IKK gamma protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Ikbkg
Gene Alias:
1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKBKG; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8517
Content And Storage:
-20°C
Form:
Liquid