PIPA517829

Amyloid Precursor Protein Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517829-Each-of-1 In Stock ₹ 41,796.06

PIPA517829 - Each of 1

₹ 41,796.06

In Stock

Quantity

1

Base Price: ₹ 41,796.06

GST (18%): ₹ 7,523.291

Total Price: ₹ 49,319.351

Antigen

Amyloid Precursor Protein

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APP

Gene Alias

A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; Amyloid b precursor protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11820, 351, 54226

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

197 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P05067, P08592, P12023

Gene Symbols

APP

Immunogen

Synthetic peptide corresponding to residues surrounding Thr668 of human APP695

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • Amyloid Precursor Protein (APP) or Amyloid beta precursor protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1
  • APP is important for neurite growth, neuronal adhesion and axonogenesis
  • APP is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms resulting from alternative splicing
  • Proteolytic cleavage of APP by beta- and gamma-secretases results in the generation of beta amyloid, which is the primary component of senile plaques
  • Senile plaques are one of the major histopathologic features of Alzheimer's disease
  • Abnormal regulation and processing of APP also plays a role in Down's syndrome, early onset familial Alzheimer's disease, and cerebral hemorrhage.

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Thermo Scientific

PIPA517829

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Antigen:
Amyloid Precursor Protein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APP

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; Amyloid b precursor protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11820, 351, 54226

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
197 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P05067, P08592, P12023

Gene Symbols:
APP

Immunogen:
Synthetic peptide corresponding to residues surrounding Thr668 of human APP695

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517832

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Antigen:
Phospho-RAC1/CDC42 (Ser71)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC42

Gene Alias:
AI747189; AL023026; AU018915; CDC42; CDC42Hs; Cell division control protein 42 homolog; cell division cycle 42; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; cell migration-inducing gene 5 protein; D5Ertd559e; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; MIG5; p21-Rac1; Rac1; Rac-1; Ras-like protein TC25; RAS-related C3 botulinum substrate 1; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); rho family, small GTP binding protein Rac1; small GTP binding protein CDC42; TC25; TC-25; TKS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5879, 998

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
94 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P60953, P63000

Gene Symbols:
CDC42, RAC1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer71 of human Rac1/cdc42

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517833

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Antigen:
Phospho-PLCB3 (Ser537)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plcb3

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; mKIAA4098; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C beta 3; phospholipase C, beta 3; phospholipase C, beta 3 (phosphatidylinositol-specific); phospholipase C-beta-3; PLC beta 3; Plcb3; PLCbeta3; PLC-beta3; PLC-beta-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5331

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q01970

Gene Symbols:
Plcb3

Immunogen:
Synthetic phosphopeptide corresponding residues surrounding pSer537 of human PLCbeta3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517834

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Antigen:
VAV1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VAV1

Gene Alias:
oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22324, 25156, 7409

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
27 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P15498, P27870, P54100

Gene Symbols:
VAV1

Immunogen:
Synthetic peptide corresponding to residues surrounding Tyr174 of human Vav

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG