PIPA517918

Phospho-MSK1 (Ser376) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517918-Each-of-1 In Stock ₹ 44,705.10

PIPA517918 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-MSK1 (Ser376)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O75582, Q8C050

Gene Symbols

Rps6ka5

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human MSK1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

Rps6ka5

Gene Alias

3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

314384, 73086, 9252

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • RPS6KA5 (MSK1) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes
  • RPS6KA5 is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes
  • Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin
  • Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression
  • In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress
  • In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential.

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Img

Thermo Scientific

PIPA517918

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Antigen:
Phospho-MSK1 (Ser376)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O75582, Q8C050

Gene Symbols:
Rps6ka5

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human MSK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Rps6ka5

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
314384, 73086, 9252

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIPA517930

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Antigen:
Tankyrase 2

Classification:
Polyclonal

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H2K2

Gene Symbols:
TNKS2

Immunogen:
Synthetic peptide sequence (RECOMBINANT2) corresponding to the internal amino acids of TNKS2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TNKS2

Gene Alias:
5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
80351

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA517931

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Antigen:
Tankyrase

Classification:
Polyclonal

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95271

Gene Symbols:
TNKS

Immunogen:
Synthetic peptide sequence (RECOMBINANT) corresponding to the N-terminus amino acids of TNKS

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TNKS

Gene Alias:
4930554K12Rik; ADP-ribosyltransferase diphtheria toxin-like 5; AI662855; ARTD5; C86528; D130072O21Rik; HGNC:11941; LOW QUALITY PROTEIN: tankyrase-1; mTNKS1; PARP5A; PARP-5a; PARPL; pART5; Poly [ADP-ribose] polymerase 5A; Poly [ADP-ribose] polymerase tankyrase-1; poly [ADP-ribose] polymerase tankyrase-1; tankyrase-1; Protein poly-ADP-ribosyltransferase tankyrase-1; TANK1; tankyrase; tankyrase 1; tankyrase I; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; TIN1; TINF1; TNKS; TNKS1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; TRF1-interacting ankyrin-related ADP-ribose polymerase 1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
8658

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA517935

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Antigen:
PGAM1/PGAM2/PGAM4

Classification:
Polyclonal

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O70250, P15259, P16290, P18669, P25113, Q8N0Y7, Q9DBJ1

Gene Symbols:
PGAM1, PGAM2, PGAM4

Immunogen:
Synthetic peptide sequence (KAMEAVAAQGKAKK) corresponding to the C-terminus amino acids of PGAM1 / PGAM2 / PGAM4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
PGAM2

Gene Alias:
2310050F24Rik; BPG-dependent PGAM 1; BPG-dependent PGAM 2; CDABP0006; D14Mgh1; dJ1000K24.1; epididymis secretory protein Li 35; GSD10; HEL-S-35; MGC88743; muscle-specific phosphoglycerate mutase; OTTHUMP00000059414; PGAM1; Pgam-1; PGAM2; PGAM3; PGAM4; PGAMA; PGAM-B; PGAMM; PGAM-M; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase 2; phosphoglycerate mutase 2 (muscle); phosphoglycerate mutase 4; phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase family 3; phosphoglycerate mutase family member 4; phosphoglycerate mutase isozyme B; Phosphoglycerate mutase isozyme M; phosphoglycerate mutase muscle-specific subunit; phosphoglycerate mutase processed protein; probable phosphoglycerate mutase 4; RP11-452K12.8

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
100154776, 100188980, 18648, 24642, 24959, 441531, 5223, 5224, 56012

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid