PIPA518098

CYB561D2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518098-Each-of-1 In Stock ₹ 44,705.10

PIPA518098 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CYB561D2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYB561D2

Gene Alias

101F6; 101F6 protein; AW049681; CYB561D2; cytochrome b-561 domain containing 2; cytochrome b561 domain-containing protein 2; cytochrome b561 family member D2; cytochrome b561 family, member D2; gene for 101F6 protein; LUCA12.2; OTTHUMP0000021067; OTTHUMP00000210675; OTTHUMP00000210676; Putative tumor suppressor protein 101F6; Transmembrane ascorbate ferrireductase; Tsp10; tumor suppressor, region 10; XXcos-LUCA11.4

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

11068

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

O14569

Gene Symbols

CYB561D2

Immunogen

Synthetic peptide sequence (VSNAYLYRKRIQP) corresponding to the C-terminus amino acids of CYB561D2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000
  • CYB561D2 (Cytochrome b561 domain-containing protein 2), also known as putative tumor suppressor protein 101F6, is a 222 amino acid highly hydrophobic protein that contains six membrane spanning domains
  • Localized to endosomes and endoplasmic reticulum of the perinuclear region, CYB561D2 contains 2 heme-binding sites, through which it reduces ferric ions
  • CYB561D2 is ubiquitously expressed, with highest levels in lung, liver and kidney
  • Though expression of CYB561D2 is abundant in normal lung bronchial epithileal cells, CYB561D2 is absent in most lung cancers
  • The gene encoding CYB561D2 maps to human chromosome 3p21.3, a region that is prone to genetic alterations and is associated with frequent and early allele loss in many human cancers
  • Exogenous expression of CYB561D2 leads to the induction of caspase-independent apoptotic and autophagic pathways, resulting in the synergistic killing of tumor cells
  • This suggests an important role for CYB561D2 as a therapeutic intervention in cancer treatment.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA518098

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Antigen:
CYB561D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYB561D2

Gene Alias:
101F6; 101F6 protein; AW049681; CYB561D2; cytochrome b-561 domain containing 2; cytochrome b561 domain-containing protein 2; cytochrome b561 family member D2; cytochrome b561 family, member D2; gene for 101F6 protein; LUCA12.2; OTTHUMP0000021067; OTTHUMP00000210675; OTTHUMP00000210676; Putative tumor suppressor protein 101F6; Transmembrane ascorbate ferrireductase; Tsp10; tumor suppressor, region 10; XXcos-LUCA11.4

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
11068

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14569

Gene Symbols:
CYB561D2

Immunogen:
Synthetic peptide sequence (VSNAYLYRKRIQP) corresponding to the C-terminus amino acids of CYB561D2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518104

--


Antigen:
PUF60

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Puf60

Gene Alias:
2410104I19Rik; 2810454F19Rik; 60 kDa poly(U)-binding-splicing factor; FBP interacting repressor; FBP-interacting repressor; FIR; FLJ31379; FUSE-binding protein-interacting repressor; LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60; poly(U) binding splicing factor 60KDa; poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60; poly-U binding splicing factor 60K; poly-U binding splicing factor 60KDa; PUF60; pyrimidine tract binding splicing factor; RNA-binding protein Siah-BP; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; ROBPI; Siah binding protein 1; siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; siah-binding protein 1; SIAHBP1; Siah-BP1; similar to fuse-binding protein-interacting repressor isoform a; VRJS

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
22827

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UHX1

Gene Symbols:
Puf60

Immunogen:
Synthetic peptide sequence (YDQERFDNSDLSA) corresponding to the C-terminus amino acids of PUF60

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518105

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Antigen:
ERC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERC1

Gene Alias:
4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST; CAST2; CAZ-associated structural protein 2; Elks; ELKS/Rab6-interacting/CAST family member 1; ERC; ERC protein 1; Erc1; ERC-1; ERC1b; FLJ31750; KIAA1081; MGC12974; mKIAA1081; OTTHUMP00000160633; Rab6 interacting protein 2; RAB6-interacting protein 2; Rab6ip2; RAB6IP2A; RAB6IP2B; RIM-Binding Protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
23085

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8IUD2

Gene Symbols:
ERC1

Immunogen:
Synthetic peptide sequence (YGSARSVGKVEPS) corresponding to the N-terminus amino acids of ERC1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518106

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Antigen:
RAD51C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD51C

Gene Alias:
BROVCA3; DNA repair protein RAD51 homolog 3; FANCO; MGC104277; R51H3; RAD51 homolog C; RAD51 paralog C; RAD51C; RAD51L2; RAD51-like protein 2; RGD1563765; yeast RAD51 homolog 3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5889

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43502

Gene Symbols:
RAD51C

Immunogen:
Synthetic peptide sequence (RGKTFRFEMQRDL) corresponding to the N-terminus amino acids of RAD51C

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG