PIPA518127

CHFR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA518127-Each-of-1 In Stock ₹ 44,705.10

PIPA518127 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CHFR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chfr

Gene Alias

5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

55743

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96EP1

Gene Symbols

Chfr

Immunogen

Synthetic peptide sequence (KFNHICEQTRFKN) corresponding to the C-terminus amino acids of CHFR

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000
  • E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons
  • Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus
  • Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome
  • Promotes the ubiquitination and subsequent degradation of AURKA and PLK1
  • Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation
  • May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer
  • Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.

Compare Similar Items

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Img

Thermo Scientific

PIPA518127

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Antigen:
CHFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chfr

Gene Alias:
5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
55743

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96EP1

Gene Symbols:
Chfr

Immunogen:
Synthetic peptide sequence (KFNHICEQTRFKN) corresponding to the C-terminus amino acids of CHFR

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518130

--


Antigen:
RNF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF2

Gene Alias:
AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; DinG; DinG protein; E3 ubiquitin-protein ligase RING2; fa19h05; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; protein DinG; RING 1B; RING 2; RING finger protein 1B; ring finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; Rnf2; wu:fa19h05; wz4556; wz4566

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
6045

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q99496

Gene Symbols:
RNF2

Immunogen:
Synthetic peptide sequence (PMELYYAPTKEHK) corresponding to the C-terminus amino acids of RNF2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518131

--


Antigen:
RNF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCGF3

Gene Alias:
2310035N15Rik; AI662857; D630042K08Rik; D6S113E; DADB-17J1.3; DKFZp686D20235; DKFZp686N0336; DONG1; E430039C14; FLJ31942; FLJ36550; FLJ43813; FSH; FSRG1; KIAA9001; MGC129075 protein; MGC129615; MGC40413; NAT; PCGF3; polycomb group ring finger 3; polycomb group RING finger protein 3; ring finger protein 3; RING finger protein 3A; RING3; RNF3; RNF3A

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
10336

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q3KNV8

Gene Symbols:
PCGF3

Immunogen:
Synthetic peptide sequence (PLLLHYRPKMDLL) corresponding to the C-terminus amino acids of PCGF3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518132

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Antigen:
RNF8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF8

Gene Alias:
3830404E21Rik; ActA binding protein 2; actA-interacting protein 37; AIP37; C3HC4-type zinc finger protein; E3 ubiquitin-protein ligase RNF8; FLJ12013; hRNF8; KIAA0646; LaXp180; OTTHUMP00000039684; ring finger protein (C3HC4 type) 8; ring finger protein 8; ring finger protein 8, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF8; RNF8; UBC13/UEV-interacting ring finger protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
9025

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O76064

Gene Symbols:
RNF8

Immunogen:
Synthetic peptide sequence (GEPGFFVTGDRAG) corresponding to the N-terminus amino acids of RNF8

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG