PIPA518372

Tyrosine Hydroxylase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518372-Each-of-1 In Stock ₹ 50,480.40

PIPA518372 - Each of 1

₹ 50,480.40

In Stock

Quantity

1

Base Price: ₹ 50,480.40

GST (18%): ₹ 9,086.472

Total Price: ₹ 59,566.872

Antigen

Tyrosine Hydroxylase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TH

Gene Alias

dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

7054

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (PFA fixed)

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P07101

Gene Symbols

TH

Immunogen

Synthetic peptide sequence (VQDELDTLAHAL) corresponding to the C-terminus amino acids of TH

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with canine and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000
  • Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine
  • In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4)
  • BH4 binds to the TH catalytic domain, resulting in enzymatic activity
  • Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated
  • These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains
  • TH is also responsible for the conversion of L-tyrosine to L-dopa
  • TH plays a key role in the physiology of adrenergic neurons
  • The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.

Compare Similar Items

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Img

Thermo Scientific

PIPA518372

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Antigen:
Tyrosine Hydroxylase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
7054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P07101

Gene Symbols:
TH

Immunogen:
Synthetic peptide sequence (VQDELDTLAHAL) corresponding to the C-terminus amino acids of TH

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518373

--


Antigen:
DOPA Decarboxylase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDC

Gene Alias:
AADC; aromatic L-amino acid decarboxylase; aromatic-L-amino acid decarboxylase; aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1644

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P20711

Gene Symbols:
DDC

Immunogen:
Synthetic peptide sequence (WEHIKELAADVL) corresponding to the C-terminus amino acids of DDC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518374

--


Antigen:
SLC6A4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC6A4

Gene Alias:
5 OCD1, 5HT transporter, 5HTT, 5-HTT, 5-HTTLPR, 5-hydroxytryptamine (serotonin) transporter, AI323329, HGNC:11050, hSERT, HTT, Na+/Cl- dependent serotonin transporter, OCD1, OTTHUMP00000163633, serotonin transporter, serotonin transporter 1, Sert, SERT1, Slc6a4, Sodium-dependent serotonin transporter, Sodium-dependent serotonin transporter (5HT transporter) (5HTT), solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), solute carrier family 6 (neurotransmitter transporter), member 4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, solute carrier family 6 member 4, solute carrier family 6, member 4

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
6532

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P31645

Gene Symbols:
SLC6A4

Immunogen:
Synthetic peptide sequence (LHQGERETWGK) corresponding to the internal amino acids of SLC6A4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518375

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Antigen:
beta-Arrestin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARRB2

Gene Alias:
AI326910; ARB2; ARR2; ARRB2; arrestin 3; arrestin beta 2; arrestin beta-2; arrestin, beta 2; arrestin-3; AW122872; BARR2; BARRES; beta arr2; beta-arrestin 2 long isoform; beta-arrestin 2 short isoform; beta-arrestin-2; Non-visual arrestin-3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
409

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P32121

Gene Symbols:
ARRB2

Immunogen:
Synthetic peptide sequence (HDHIPLPRPQS) corresponding to the internal amino acids of ARRB2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG