PIPA518414

TRPC6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518414-Each-of-1 In Stock ₹ 43,079.46

PIPA518414 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

TRPC6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Trpc6

Gene Alias

AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

7225

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9Y210

Gene Symbols

Trpc6

Immunogen

Synthetic peptide sequence (EKLSMEPNQEETN) corresponding to the C-terminus amino acids of TRPC6

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, human, and porcine based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000
  • Trpc6 forms a receptor-activated calcium channel in the cell membrane
  • The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
  • Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
  • Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
  • Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the &quotecanonical TRP&quote (TRPC) family
  • The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
  • Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
  • When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
  • Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
  • There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
  • Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.

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PIPA518414

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Antigen:
TRPC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trpc6

Gene Alias:
AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
7225

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9Y210

Gene Symbols:
Trpc6

Immunogen:
Synthetic peptide sequence (EKLSMEPNQEETN) corresponding to the C-terminus amino acids of TRPC6

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518418

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Antigen:
LDB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LDB3

Gene Alias:
AW742271; cardiomyopathy, dilated 1C (autosomal dominant); CMD1C; CMH24; CMPD3; cypher; FLJ35865; HGNC:15710; KIAA01613; KIAA0613; LDB3; LDB3Z1; LDB3Z4; LIM domain binding 3; LIM domain-binding protein 3; LVNC3; MFM4; ORACLE; oracle protein; PDLIM6; PDZ and LIM domain 6; PDZ-LIM domain protein; protein cypher; Protein oracle; RGD1564875; ZASP; Z-band alternatively spliced PDZ motif protein; Z-band alternatively spliced PDZ-motif protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
11155

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75112

Gene Symbols:
LDB3

Immunogen:
Synthetic peptide sequence (KSQNKPEDEADE) corresponding to the internal amino acids of LDB3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518419

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Antigen:
GOLGA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Golga3

Gene Alias:
5330413L04; 5430416E01Rik; AI449376; AW490576; G1-499-14; GCP170; GOLGA3; golgi autoantigen, golgin subfamily a, 3; golgi complex-associated protein of 170 kDa; Golgi membrane associated protein; Golgi peripheral membrane protein; golgin A3; Golgin subfamily A member 3; Golgin-160; golgin-165; HGNC:4426; male enhanced antigen-2; male-enhanced antigen 2; Mea2; MEA-2; Mea2/Golga3; repro27; SY2/SY10 protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2802

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q08378

Gene Symbols:
Golga3

Immunogen:
Synthetic peptide sequence (HSQSRASKEGPGE) corresponding to the C-terminus amino acids of GOLGA3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518420

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Antigen:
MAOA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAOA

Gene Alias:
1110061B18Rik; AA407771; Amine oxidase [flavin-containing] A; HGNC:6833; Mao; MAOA; MAO-A; monoamine oxidase A; monoamine oxidase type A; RP1-201D17__B.2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
4128

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P21397

Gene Symbols:
MAOA

Immunogen:
Synthetic peptide sequence (DAPWEAQHADKWDK) corresponding to the internal amino acids of MAOA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG