PIPA518425

PCK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518425-Each-of-1 In Stock ₹ 44,705.10

PIPA518425 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PCK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PCK1

Gene Alias

AI265463; GTP; HGNC:8724; MGC22652; PCK; Pck1; Pck-1; PE PEPCKC; PEP carboxykinase; PEPCK; PEPCK1; PEPCKC; PEPCK-C; phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase 1, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic (GTP); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase; RATPEPCK

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

5105

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P35558

Gene Symbols

PCK1

Immunogen

Synthetic peptide sequence (HVNWFRKDKEGK) corresponding to the internal amino acids of PCK1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000
  • Phosphoenolpyruvate Carboxykinase 1 (PCK1) is a main control point for the regulation of gluconeogenesis
  • During gluconeogenesis PCK1 acts as the rate-limiting enzyme
  • PCK1 regulates the formation and maintenance of memory CH8(+) T-cells via gluconeogenesis
  • PCK1 aids in controlling the levels of metabolic intermediates in the citric acid cycle by regulating cataplerosis and anaplerosis
  • When glucose levels are high, PCK1 catalyzes the cataplerotic conversion of oxaloacetate to phosphoenolpyruvate (PEP)
  • When they are low it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate
  • When phosphorylated at Ser-90 by AKT1, PCK1 acts as a protein kinase by reducing the binding affinity to oxaloacetate and promotes an atypical serine protein kinase activity using GTP as the donor
  • This activity regulates lipogenesis by disrupting the interaction between INSIG proteins and SCAP and promoting nuclear translocation of SREBP proteins and transcription of lipogenesis-related genes
  • An important paralog of this gene is PCK2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA518425

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Antigen:
PCK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCK1

Gene Alias:
AI265463; GTP; HGNC:8724; MGC22652; PCK; Pck1; Pck-1; PE PEPCKC; PEP carboxykinase; PEPCK; PEPCK1; PEPCKC; PEPCK-C; phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase 1, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic (GTP); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase; RATPEPCK

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5105

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P35558

Gene Symbols:
PCK1

Immunogen:
Synthetic peptide sequence (HVNWFRKDKEGK) corresponding to the internal amino acids of PCK1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518426

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Antigen:
PCK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCK2

Gene Alias:
1810010O14Rik; 9130022B02Rik; HGNC:8725; PCK2; PEP carboxykinase; PEPCK; PEPCK2; PEPCK-M; Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; phosphoenolpyruvate carboxykinase 2 (mitochondrial); phosphoenolpyruvate carboxykinase 2, mitochondrial; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5106, 74551

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q16822, Q8BH04

Gene Symbols:
PCK2

Immunogen:
Synthetic peptide sequence (KPWKPGDKEPCAH) corresponding to the internal amino acids of PCK2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518427

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Antigen:
Cannabinoid Receptor 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNR1

Gene Alias:
brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1268

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P21554

Gene Symbols:
CNR1

Immunogen:
Synthetic peptide sequence (HTSEDGKVQVTRPDQ) corresponding to the internal amino acids of CNR1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518428

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Antigen:
CNR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNR2

Gene Alias:
Cannabinoid Receptor 2; cannabinoid receptor 2 (macrophage); CB2; CB-2; CB2 receptor; CB2A; CB2B; CB2C; CB2R; CB2-R; CNR2; CNR2C; CNR3; CX5; HCB2; HGNC:2160; OTTHUMP00000044841; peripheral cannabinoid receptor; rCB2; RP11-4M23.1; testis-dominant CNR2 isoform CB2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1269

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P34972

Gene Symbols:
CNR2

Immunogen:
Synthetic peptide sequence (TETEADGKITPWPD) corresponding to the C-terminus amino acids of CNR2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG