PIPA518463

Cyclophilin A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA518463-Each-of-1 In Stock ₹ 47,614.14

PIPA518463 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

Cyclophilin A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ppia

Gene Alias

2700098C05; Cphn; CYCA; cyclophilin; Cyclophilin A; Cyclosporin A-binding protein; CyP A; CyP-18; CYPA; CyP-A; CYPH; EC 5.2.1.8; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; HGNC:9253; I79_011869; MGC117158; MGC12404; MGC23397; p1B15; p31; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase; PPIase A; rotamase; rotamase A; SP18; T cell cyclophilin

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

5478

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P62937

Gene Symbols

Ppia

Immunogen

Synthetic peptide sequence (ERFGSRNGKTSKK) corresponding to the internal amino acids of PPIA

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000
  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins that bind FK506 are termed FK506 Binding Proteins (FKBPs) and those that bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins
  • Within the cyclophilin family, there are several different proteins which show a high degree of homology including CyPA, CyPB and CyPC
  • CyPA, also termed CyP-18, is the most abundant and ubiquitous cyclophilin found in all vertebrate tissues and is present in T-cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA518463

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Antigen:
Cyclophilin A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppia

Gene Alias:
2700098C05; Cphn; CYCA; cyclophilin; Cyclophilin A; Cyclosporin A-binding protein; CyP A; CyP-18; CYPA; CyP-A; CYPH; EC 5.2.1.8; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; HGNC:9253; I79_011869; MGC117158; MGC12404; MGC23397; p1B15; p31; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase; PPIase A; rotamase; rotamase A; SP18; T cell cyclophilin

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5478

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62937

Gene Symbols:
Ppia

Immunogen:
Synthetic peptide sequence (ERFGSRNGKTSKK) corresponding to the internal amino acids of PPIA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518464

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Antigen:
VPS25

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VPS25

Gene Alias:
1110020N13Rik; AW107467; D11Wsu68e; dermal papilla-derived protein 9; DERP9; Eap20; ELL-associated protein of 20 kDa; ESCRT-II complex subunit VPS25; FAP20; HGNC:28122; hVps25; MGC10540; vacuolar protein sorting 25 (yeast); vacuolar protein sorting 25 homolog; vacuolar protein sorting 25 homolog (S. cerevisiae); vacuolar protein-sorting-associated protein 25; VPS25

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
681059, 84313

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P0C0A1, Q9BRG1

Gene Symbols:
VPS25

Immunogen:
Synthetic peptide sequence (QPNVDTRQKQ) corresponding to the internal amino acids of VPS25

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518465

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Antigen:
ERG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Erg

Gene Alias:
avian erythroblastosis virus E-26 (v-ets) oncogene related; D030036I24Rik; ERG; ERG, ETS transcription factor; ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; Erg-3; erythroblast transformation-specific transcription factor ERG variant 10; ETS transcription factor ERG; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; p55; TMPRSS2/ERG fusion; transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); transcriptional regulator ERG; LOW QUALITY PROTEIN: transcriptional regulator ERG; Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2078

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P11308

Gene Symbols:
Erg

Immunogen:
Synthetic peptide sequence (PNTRLPTSHMPSH) corresponding to the C-terminus amino acids of ERG

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518466

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Antigen:
TRIM5 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trim5

Gene Alias:
EG667823; Gm8833; HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5; Trim5 alpha; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5 gamma isoform; tripartite motif-containing 5/cyclophilin A fusion protein; tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
85363

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9C035

Gene Symbols:
Trim5

Immunogen:
Synthetic peptide sequence (CNIEKNENYQPK) corresponding to the internal amino acids of TRIM5

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG