PIPA518562
STAT3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA518562-Each-of-1 | In Stock | ₹ 47,357.46 |
PIPA518562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,357.46
GST (18%): ₹ 8,524.343
Total Price: ₹ 55,881.803
Antigen
STAT3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
20848, 6774
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P40763, P42227
Gene Symbols
STAT3
Immunogen
Synthetic peptide sequence (CRPESQEHPEADP) corresponding to the internal amino acids of STAT3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with canine, mouse and rat based on sequence homology
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
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Antigen: STAT3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 20848, 6774
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P40763, P42227
Gene Symbols: STAT3
Immunogen: Synthetic peptide sequence (CRPESQEHPEADP) corresponding to the internal amino acids of STAT3
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
STAT3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 6774
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P40763, P42227
Gene Symbols:
STAT3
Immunogen:
Synthetic peptide sequence (CRPESQEHPEADP) corresponding to the internal amino acids of STAT3
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PTEN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TPTE
Gene Alias: Cancer/testis antigen 44; CT44; Pten2; PTEN-related tyrosine phosphatase; Putative tyrosine-protein phosphatase TPTE; tensin, putative protein-tyrosine phosphatase; TPTE; Transmembrane phosphatase with tensin homology; tumor antigen BJ-HCC-5
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 7179
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P56180
Gene Symbols: TPTE
Immunogen: Synthetic peptide sequence (ERRTDKTHSEKFQ) corresponding to the internal amino acids of TPTE
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTEN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TPTE
Gene Alias:
Cancer/testis antigen 44; CT44; Pten2; PTEN-related tyrosine phosphatase; Putative tyrosine-protein phosphatase TPTE; tensin, putative protein-tyrosine phosphatase; TPTE; Transmembrane phosphatase with tensin homology; tumor antigen BJ-HCC-5
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
7179
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P56180
Gene Symbols:
TPTE
Immunogen:
Synthetic peptide sequence (ERRTDKTHSEKFQ) corresponding to the internal amino acids of TPTE
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SNX26
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARHGAP33
Gene Alias: ARHGAP33; AW324378; FLJ39019; neurite outgrowth multiadaptor RhoGAP protein; NOMA-GAP; Rho GTPase activating protein 33; rho GTPase-activating protein 33; rho GTPase-activating protein 33; LOW QUALITY PROTEIN: rho GTPase-activating protein 33; rho-type GTPase-activating protein 33; Snx26; sorting nexin 26; sorting nexin-26; Tc10/CDC42 GTPase-activating protein; TCGAP
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 115703
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: O14559
Gene Symbols: ARHGAP33
Immunogen: Synthetic peptide sequence (ARSTDSLDGPGE) corresponding to the N-terminus amino acids of SNX26
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SNX26
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARHGAP33
Gene Alias:
ARHGAP33; AW324378; FLJ39019; neurite outgrowth multiadaptor RhoGAP protein; NOMA-GAP; Rho GTPase activating protein 33; rho GTPase-activating protein 33; rho GTPase-activating protein 33; LOW QUALITY PROTEIN: rho GTPase-activating protein 33; rho-type GTPase-activating protein 33; Snx26; sorting nexin 26; sorting nexin-26; Tc10/CDC42 GTPase-activating protein; TCGAP
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
115703
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O14559
Gene Symbols:
ARHGAP33
Immunogen:
Synthetic peptide sequence (ARSTDSLDGPGE) corresponding to the N-terminus amino acids of SNX26
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: KV3.3 (KCNC3)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KCNC3
Gene Alias: KCNC3; Kcr2-3; KShIIID; KV3.3; LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily C member 3; potassium channel, voltage gated Shaw related subfamily C, member 3; potassium channel, voltage gated Shaw-related subfamily C, member 3; potassium voltage gated channel, Shaw-related subfamily, member 3; potassium voltage-gated channel subfamily C member 3; potassium voltage-gated channel, Shaw-related subfamily, member 3; SCA13; Shaw type potassium channel Kv3.3; Shaw-related voltage-gated potassium channel protein 3; voltage-gated potassium channel protein KV3.3; voltage-gated potassium channel subunit Kv3.3
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 3748
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q14003
Gene Symbols: KCNC3
Immunogen: Synthetic peptide sequence (KPGPPSFLPDLNAN) corresponding to the C-terminus amino acids of KCNC3
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
KV3.3 (KCNC3)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KCNC3
Gene Alias:
KCNC3; Kcr2-3; KShIIID; KV3.3; LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily C member 3; potassium channel, voltage gated Shaw related subfamily C, member 3; potassium channel, voltage gated Shaw-related subfamily C, member 3; potassium voltage gated channel, Shaw-related subfamily, member 3; potassium voltage-gated channel subfamily C member 3; potassium voltage-gated channel, Shaw-related subfamily, member 3; SCA13; Shaw type potassium channel Kv3.3; Shaw-related voltage-gated potassium channel protein 3; voltage-gated potassium channel protein KV3.3; voltage-gated potassium channel subunit Kv3.3
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
3748
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q14003
Gene Symbols:
KCNC3
Immunogen:
Synthetic peptide sequence (KPGPPSFLPDLNAN) corresponding to the C-terminus amino acids of KCNC3
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG