PIPA518873

APOBEC3C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518873-Each-of-1 In Stock ₹ 44,191.74

PIPA518873 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

APOBEC3C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOBEC3C

Gene Alias

A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

27350

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9NRW3

Gene Symbols

APOBEC3C

Immunogen

Synthetic peptide sequence (RLLKRRLRESLQ) corresponding to the C-terminus amino acids of APOBEC3C

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1,000
  • APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
  • The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
  • Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
  • Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
  • Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
  • Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
  • This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA518873

--


Antigen:
APOBEC3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOBEC3C

Gene Alias:
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
27350

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9NRW3

Gene Symbols:
APOBEC3C

Immunogen:
Synthetic peptide sequence (RLLKRRLRESLQ) corresponding to the C-terminus amino acids of APOBEC3C

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518874

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Antigen:
Pyruvate Carboxylase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PC

Gene Alias:
EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5091

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P11498

Gene Symbols:
PC

Immunogen:
Synthetic peptide sequence (KFKEVKKAYVEANQ) corresponding to the internal amino acids of PC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518875

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Antigen:
RAB8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB8A

Gene Alias:
AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
4218

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P61006

Gene Symbols:
RAB8A

Immunogen:
Synthetic peptide sequence (NQGVKITPDQQKR) corresponding to the C-terminus amino acids of RAB8A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518876

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Antigen:
RAB17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rab17

Gene Alias:
AW413472; Rab17; RAB17, member RAS oncogene family; ras-related protein Rab-17; RGD1562478

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
19329

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P35292

Gene Symbols:
Rab17

Immunogen:
Synthetic peptide sequence (RKDSFHKAQQWLED) corresponding to the internal amino acids of Rab17

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG