PIPA518919

ARK5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA518919-Each-of-1 In Stock ₹ 47,443.02

PIPA518919 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

ARK5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUAK1

Gene Alias

AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

9891

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

O60285

Gene Symbols

NUAK1

Immunogen

Synthetic peptide sequence (QNRPRPQYLKRYRNR) corresponding to the internal amino acids of NUAK1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000
  • NUAK1 (ARK5) is a serine/threonine kinase that plays a role in many cellular functions
  • The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm)
  • Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability
  • Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex
  • Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1
  • May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53
  • May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1
  • Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR
  • Regulates UV radiation-induced DNA damage response mediated by CDKN1A
  • In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.

Compare Similar Items

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Thermo Scientific

PIPA518919

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Antigen:
ARK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUAK1

Gene Alias:
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
9891

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O60285

Gene Symbols:
NUAK1

Immunogen:
Synthetic peptide sequence (QNRPRPQYLKRYRNR) corresponding to the internal amino acids of NUAK1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518920

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Antigen:
CHRNB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHRNB2

Gene Alias:
[b]2-nAchR; acetylcholine receptor; acetylcholine receptor beta 2 neural; acetylcholine receptor, nicotinic, beta 2 (neuronal); Acrb2; Acrb-2; beta2 human neuronal nicotinic acetylcholine receptor; C030030P04Rik; cholinergic receptor; cholinergic receptor nicotinic beta 2 subunit; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; CHRNB2; EFNL3; nAChRB2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2; neuronal acetylcholine receptor, beta 2; neuronal nicotinic acetylcholine receptor; neuronal nicotinic acetylcholine receptor beta 2; nicotinic acetylcholine receptor beta 2 subunit

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1141

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P17787

Gene Symbols:
CHRNB2

Immunogen:
Synthetic peptide sequence (QPRHHCARQRLR) corresponding to the internal amino acids of CHRNB2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518921

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Antigen:
NTF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NTF4

Gene Alias:
2900040K06Rik, AI462899, GLC10, GLC1O, neurotrophic factor 4, neurotrophic factor 5, neurotrophin 4, Neurotrophin 4/5, neurotrophin 5, Neurotrophin 5 (neurotrophin 4/5), neurotrophin 5 (neurotrophin 4/5), neurotrophin-4, Neurotrophin-5, neutrophic factor 4, Neutrophic factor 5, NT4, NT-4, NT4/5, NT-4/5, NT4/NT5, NT4P, NT5, NT-5, Ntf4, Ntf5, Ntf-5

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
4909

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P34130

Gene Symbols:
NTF4

Immunogen:
Synthetic peptide sequence (FETRCKADNAEEG) corresponding to the internal amino acids of NTF5

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA518922

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Antigen:
ASNA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GET3

Gene Alias:
1810048H22Rik; ARSA; arsA arsenite transporter, ATP-binding, homolog 1; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ARSA1; ARSA-I; Arsenical pump-driving ATPase; Arsenical resistance ATPase; arsenite-stimulated ATPase; arsenite-translocating ATPase; Arsenite-transporting ATPase; asna1; ASNA-I; ATPase asna1; ATPase GET3; GET3; guided entry of tail-anchored proteins factor 3, ATPase; hARSA-I; hASNA-I; MGC3821; si:dkey-121b10.2; Transmembrane domain recognition complex 40 kDa ATPase subunit; TRC40; wu:fd05d03; zgc:56540; zgc:56540 protein; zgc:86799

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
288919, 439, 56495

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43681, O54984

Gene Symbols:
GET3

Immunogen:
Synthetic peptide sequence (PHEVRGADKVNT) corresponding to the internal amino acids of ASNA1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG