PIPA519068

NOXA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519068-Each-of-1 In Stock ₹ 44,705.10

PIPA519068 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NOXA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PMAIP1

Gene Alias

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

5366

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q13794

Gene Symbols

PMAIP1

Immunogen

Synthetic peptide sequence (TQLRRFGDKLNFRQK) corresponding to the internal amino acids of PMAIP1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000
  • Apoptosis is related to many diseases and development
  • The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
  • A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
  • Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
  • X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
  • Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
  • Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
  • Noxa and PUMA may represent direct mediators of p53-induced apoptosis
  • Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

Compare Similar Items

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Img

Thermo Scientific

PIPA519068

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Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5366

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13794

Gene Symbols:
PMAIP1

Immunogen:
Synthetic peptide sequence (TQLRRFGDKLNFRQK) corresponding to the internal amino acids of PMAIP1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519069

--


Antigen:
EVL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EVL

Gene Alias:
AI528774; ena/vasodilator-stimulated phosphoprotein-like; Ena/VASP-like protein; Enah/Vasp-like; Ena-vasodilator stimulated phosphoprotein; Evl; Rnb6

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
51466

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UI08

Gene Symbols:
EVL

Immunogen:
Synthetic peptide sequence (SQPPNSSEAGRKP) corresponding to the internal amino acids of EVL

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519071

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Antigen:
TRPC4AP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPC4AP

Gene Alias:
4833429F06Rik; C20orf188; D2Ertd113e; hypothetical protein; mFLJ00177; PPP1R158; protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; short transient receptor potential channel 4 associated protein; short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor potential cation channel subfamily C member 4 associated protein; transient receptor potential cation channel, subfamily C, member 4 associated protein; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; Trpc4ap; trpc4-associated protein; Trrp4ap; TRUSS; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
26133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8TEL6

Gene Symbols:
TRPC4AP

Immunogen:
Synthetic peptide sequence (KLTQETTYPNTYIFD ) corresponding to the internal amino acids of TRPC4AP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519073

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Antigen:
PCSK9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCSK9

Gene Alias:
AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
255738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8NBP7

Gene Symbols:
PCSK9

Immunogen:
Synthetic peptide sequence (TRFHRQASKCDSHGT) corresponding to the internal amino acids of PCSK9

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG