PIPA519155

GGCX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA519155-Each-of-1 In Stock ₹ 44,790.66

PIPA519155 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

GGCX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ggcx

Gene Alias

FLJ26629; Gamma-glutamyl carboxylase; GC; GGCX; Peptidyl-glutamate 4-carboxylase; vitamin K gamma glutamyl carboxylase; Vitamin K-dependent gamma-carboxylase; VKCFD1

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

2677

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P38435

Gene Symbols

Ggcx

Immunogen

Synthetic peptide sequence (PPESNPDPVHSE) corresponding to the C-terminus amino acids of GGCX

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with canine based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000
  • GGCX (gamma-glutamyl carboxylase), also known as GC or VKCFD1 (Vitamin K-dependent gamma-carboxylase), is a 758 amino acid multi-pass membrane protein
  • Localized to the membrane of the endoplasmic reticulum, GGCX functions to mediate the vitamin K-dependent carboxylation of glutamate residues on target proteins, thereby producing calcium binding gamma-carboxyglutamate (Gla) residues on these proteins and simultaneously converting vitamin K to vitamin K epoxide
  • GGCX exists as a monomer and, via its ability to modify glutamate residues, it accomplishes the post-translational changes that are necessary for the activity of all vitamin K-dependent proteins (such as blood coagulation and bone matrix proteins)
  • Defects in the gene encoding GGCX are the cause of combined deficiency of vitamin K-dependent clotting factors 1 (VKCFD1) and PXE-like disorder with multiple coagulation factor deficiency, both of which are characterized by abnormal skin, blood or bone function.

Compare Similar Items

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Thermo Scientific

PIPA519155

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Antigen:
GGCX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ggcx

Gene Alias:
FLJ26629; Gamma-glutamyl carboxylase; GC; GGCX; Peptidyl-glutamate 4-carboxylase; vitamin K gamma glutamyl carboxylase; Vitamin K-dependent gamma-carboxylase; VKCFD1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2677

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P38435

Gene Symbols:
Ggcx

Immunogen:
Synthetic peptide sequence (PPESNPDPVHSE) corresponding to the C-terminus amino acids of GGCX

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519158

--


Antigen:
IREB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IREB2

Gene Alias:
ACO3; D9Ertd85e; FLJ23381; im:7153062; Ireb2; IRE-BP 2; IREBP2; Iron regulatory protein 2; iron responsive element binding protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; Iron-responsive element-binding protein 2-like protein; IRP2; IRP2AD

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3658, 64602, 64831

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P48200, Q62751, Q811J3

Gene Symbols:
IREB2

Immunogen:
Synthetic peptide sequence (SIHYEGSEYKLSHGS) corresponding to the internal amino acids of IREB2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA519159

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Antigen:
JAM-A (CD321)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
F11r

Gene Alias:
9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
16456, 50848

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O88792, Q9Y624

Gene Symbols:
F11r

Immunogen:
Synthetic peptide sequence (QPSARSEGEFKQTS) corresponding to the C-terminus amino acids of F11R

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA519160

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Antigen:
JAM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAM2

Gene Alias:
1110002N23Rik; 2410030G21Rik; 2410167M24Rik; AU016127; C21orf43; CD322; Jam2; JAM-2; JAMB; JAM-B; JAM-IT/VE-JAM; Jcam2; junction adhesion molecule 2; junction adhesion molecule B; junction cell adhesion molecule 2; junctional adhesion molecule 2; Junctional adhesion molecule B; PRO245; RP23-253E17.2; UNQ219/PRO245; Vascular endothelial junction-associated molecule; VEJAM; VE-JAM

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
58494

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P57087

Gene Symbols:
JAM2

Immunogen:
Synthetic peptide sequence (QRKGYFSKETSFQ) corresponding to the internal amino acids of JAM2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG