PIPA519201

TET2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA519201-Each-of-1 In Stock ₹ 44,705.10

PIPA519201 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TET2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TET2

Gene Alias

Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

54790

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q6N021

Gene Symbols

TET2

Immunogen

Synthetic peptide sequence (PHPQSNNDQQREGSF) corresponding to the internal amino acids of TET2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with canine and mouse based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000
  • TET2 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydromethylcytosine (5hmC) and plays a key role in active DNA demethylation
  • TET2 has a preference for 5-hydroxymethylcytosine in CpG motifs
  • It mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC) and conversion of 5fC to 5-carboyxlcytosine (5caC)
  • Conversion of 5mC into 5hmC, 5fC, and 5caC probably constitutes the first step in cytonsine demethylation
  • In addition to TET2’s role in DNA demethylation, it is also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT
  • Mutations in the genes can result in Polycythemia vera and Myelodysplastic syndrome.

Compare Similar Items

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Thermo Scientific

PIPA519201

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Antigen:
TET2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
54790

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6N021

Gene Symbols:
TET2

Immunogen:
Synthetic peptide sequence (PHPQSNNDQQREGSF) corresponding to the internal amino acids of TET2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519202

--


Antigen:
AAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AAK1

Gene Alias:
5530400K14Rik; 9630042K20; Aak1; Adaptor-associated kinase 1; AP2 associated kinase 1; AP2-associated protein kinase 1; AU067724; AU067726; BC028270; C79663; D6Ertd245e; DKFZp686F03202; DKFZp686K16132; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; KIAA1048; MGC138170; MGC164568; MGC164570; mKIAA1048; R75501; RGD1563580

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
22848

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q2M2I8

Gene Symbols:
AAK1

Immunogen:
Synthetic peptide sequence (GSPRTSQQNVYNPSE) corresponding to the internal amino acids of AAK1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519205

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Antigen:
KCNN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kcnn2

Gene Alias:
apamin-sensitive small-conductance Ca2+-activated potassium channel; fri; hSK2; KCa2.2; KCNN2; potassium calcium-activated channel subfamily N member 2; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel type2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; SK2; SKCa 2; SKCa2; small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel 2; small conductance calcium-activated potassium channel protein 2; small conductance calcium-activated potassium channel protein 2-like; small conductance calcium-activated potassium channel subfamily N member 2; small conductance potassium channel type 2; small conductance potassium channel type2; small conductance potassium channel type2 variant2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H2S1

Gene Symbols:
Kcnn2

Immunogen:
Synthetic peptide sequence (ESYDKHVTYNAER) corresponding to the internal amino acids of KCNN2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA519206

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Antigen:
GAL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gal

Gene Alias:
ETL8; GAL; GAL1; Galanin; galanin and GMAP prepropeptide; Galanin message-associated peptide; Galanin peptides; galanin prepropeptide; galanin/GMAP prepropeptide; galanin-message-associated peptide; galanin-related peptide; GAL-GMAP; GALN; GLNN; GMAP; MGC40167; preprogalanin

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
14419, 29141, 51083

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10683, P22466, P47212

Gene Symbols:
Gal

Immunogen:
Synthetic peptide sequence (HRSFSDKNGLTSK) corresponding to the internal amino acids of GAL

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG