PIPA519246
Mesothelin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519246-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA519246 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Mesothelin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MSLN
Gene Alias
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
10232
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q13421
Gene Symbols
MSLN
Immunogen
Synthetic peptide sequence (CPSGKKAREIDES) corresponding to the internal amino acids of MSLN
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000
- Originally identified as a differentiation antigen of mesotheliomas, ovarian cystadenocarcinomas, and pancreatic adenocarcinomas, Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored, cell-surface glycoprotein predominantly secreted by cells of the mesothelium
- Although Mesothelin is expressed at restricted levels by normal mesothelial cells of the pleural,pericardial, and peritoneal membranes, aberrant expression has been documented in the aforementioned cancers, as well as in endometriod uterine adenocarcinomas and squamous cell carcinomas of the esophagus, stomach, lung, and cervix
- Proteolytic cleavage of Mesothelin yields a soluble, polypeptide fragment designated megakaryocyte potentiating factor (MPF) based on its ability to stimulate megakaryocyte colony-forming activity of murine interleukin-3 in murine bone marrow cell cultures
- Originally isolated from the HPC-Y5 pancreatic cell line, MPF has been suggested to play a role in the proliferation and differentiation of megakaryoctyes, and the regulation of resultant platelet production
- While the biological functions of both Mesothelin and MPF remain speculative, high-levels of expression in cancerous tissues compared to limited distribution in normal tissues strongly suggests their involvement in tumorigenesis
- Both have been demonstrated to promote tumor cell proliferation, migration,anchorage-independent growth, and tumor progression; demonstrating their involvement in heterotypic cell adhesion and the metastatic spread of cancer.
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Antigen: Mesothelin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: Synthetic peptide sequence (CPSGKKAREIDES) corresponding to the internal amino acids of MSLN
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Mesothelin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
Synthetic peptide sequence (CPSGKKAREIDES) corresponding to the internal amino acids of MSLN
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MICS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GHITM
Gene Alias: 1010001P14Rik; C77840; dermal papilla-derived protein 2; DERP2; DKFZp566C0746; FLJ26584; GHITM; growth hormone inducible transmembrane protein; growth hormone-inducible transmembrane protein; growth hormone-inducible transmembrane protein-like protein; HSPC282; MICS1; mitochondrial morphology and cristae structure 1; My021; PTD010; similar to Dermal papilla derived protein 2; Tmbim5; transmembrane BAX inhibitor motif containing 5; transmembrane BAX inhibitor motif-containing protein 5; UNQ244/PRO281
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 27069
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9H3K2
Gene Symbols: GHITM
Immunogen: Synthetic peptide sequence (PSREYATKTRIGIR) corresponding to the internal amino acids of GHITM
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MICS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GHITM
Gene Alias:
1010001P14Rik; C77840; dermal papilla-derived protein 2; DERP2; DKFZp566C0746; FLJ26584; GHITM; growth hormone inducible transmembrane protein; growth hormone-inducible transmembrane protein; growth hormone-inducible transmembrane protein-like protein; HSPC282; MICS1; mitochondrial morphology and cristae structure 1; My021; PTD010; similar to Dermal papilla derived protein 2; Tmbim5; transmembrane BAX inhibitor motif containing 5; transmembrane BAX inhibitor motif-containing protein 5; UNQ244/PRO281
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
27069
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9H3K2
Gene Symbols:
GHITM
Immunogen:
Synthetic peptide sequence (PSREYATKTRIGIR) corresponding to the internal amino acids of GHITM
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Cystatin 8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CST8
Gene Alias: CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 10047
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: O60676
Gene Symbols: CST8
Immunogen: Synthetic peptide sequence (STNEICAIQENSK) corresponding to the internal amino acids of CST8
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cystatin 8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CST8
Gene Alias:
CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
10047
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O60676
Gene Symbols:
CST8
Immunogen:
Synthetic peptide sequence (STNEICAIQENSK) corresponding to the internal amino acids of CST8
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Cystatin 8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CST8
Gene Alias: CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 10047
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: O60676
Gene Symbols: CST8
Immunogen: Synthetic peptide sequence (DPKKNETGVLRK) corresponding to the internal amino acids of CST8
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cystatin 8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CST8
Gene Alias:
CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
10047
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O60676
Gene Symbols:
CST8
Immunogen:
Synthetic peptide sequence (DPKKNETGVLRK) corresponding to the internal amino acids of CST8
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG