PIPA519262

LAIR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519262-Each-of-1 In Stock ₹ 44,705.10

PIPA519262 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

LAIR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LAIR1

Gene Alias

5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

3903

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q6GTX8

Gene Symbols

LAIR1

Immunogen

Synthetic peptide sequence (NDTEDVSQASPSE) corresponding to the internal amino acids of LAIR1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1,000
  • LAIR1 (CD305) functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells
  • Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11
  • It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation
  • May also play its inhibitory role independently of SH2-containing phosphatases
  • Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta
  • Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion
  • Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells
  • Inhibits the differentiation of peripheral blood precursors towards dendritic cells.

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Thermo Scientific

PIPA519262

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Antigen:
LAIR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAIR1

Gene Alias:
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3903

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6GTX8

Gene Symbols:
LAIR1

Immunogen:
Synthetic peptide sequence (NDTEDVSQASPSE) corresponding to the internal amino acids of LAIR1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519263

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Antigen:
MMP12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mmp12

Gene Alias:
3.4.24.65; AV378681; HME; Macrophage elastase; macrophage metalloelastase; macrophage-metalloelastase; matrix metallo protease; matrix metallopeptidase 12; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12; matrix metalloproteinase 12 (macrophage elastase); matrix metalloproteinase-12; ME; MGC138506; MME; Mmel; MMP; Mmp12; MMP-12; MMPs

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
4321

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P39900

Gene Symbols:
Mmp12

Immunogen:
Synthetic peptide sequence (RPKTSVNLISS) corresponding to the internal amino acids of MMP12

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519264

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Antigen:
HOXA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HOXA1

Gene Alias:
BSAS; early retinoic acid 1; ERA1; homeo box A1; homeobox 1F; homeobox A1; homeobox protein Hox-1.6; homeobox protein Hox-1F; Homeobox protein Hox-A1; homeoboxless protein ERA-1-399; homeotic protein ERA-1-993; Hox 1.6-like protein; HOX A1 homeodomain protein; HOX1; Hox-1.6; HOX1F; HOXA 1; HOXA1; HOXA-1; lab-like protein; MGC45232; NEWGENE_2812

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3198

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49639

Gene Symbols:
HOXA1

Immunogen:
Synthetic peptide sequence (QPATYQTSGN) corresponding to the internal amino acids of HOXA1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA519265

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Antigen:
CRISP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRISP2

Gene Alias:
Cancer/testis antigen 36; CRISP2; CRISP-2; Crisp2l; CT36; cysteine rich secretory protein 2; cysteine-rich secretory protein 2; cysteine-rich secretory protein 2-like; GAPDL5; glyceraldehyde-3-phosphate dehydrogenase-like 5; MGC111136; OTTHUMP00000016589; testicular tissue protein Li 43; testis specific gene 1; testis specific protein 1; testis specific protein 1 (probe H4-1 p3-1); testis-specific protein TPX-1; TPX1; Tpx-1; TSP1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
7180

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P16562

Gene Symbols:
CRISP2

Immunogen:
Synthetic peptide sequence (QHSDPEDRKTSTR) corresponding to the internal amino acids of CRISP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG