PIPA519296
MLLT10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519296-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA519296 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MLLT10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MLLT10
Gene Alias
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
361285, 8028
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P55197
Gene Symbols
MLLT10
Immunogen
Synthetic peptide sequence (RLEDTTARFTNAN) corresponding to the internal amino acids of MLLT10
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Description
- This antibody is predicted to react with bovine, canine, human and mouse based on sequence homology
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000
- Translocations affecting chromosome 11q23 involve many partner chromosome regions and occur in various leukemias
- The 11q23 gene involved in the translocations is MLL
- MLLT10 is the partner gene to MLL1 involved in t(10;11)(p12;q23) translocations
- In an analysis of two leukemia patients, the in t(10;11)(p12;q23) translocation fuses MLL1, a SET domain containg histone methyltransferase, to the MLLT10 gene
- The MLLT10 gene encodes a predicted 1,027-amino acid protein containing an N-terminal zinc finger and a C-terminal leucine zipper domain
- The MLLT10 gene is one of the few MLL partner genes to be independently rearranged with a third gene in leukemia, the CALM gene in the t(10;11)(p12;q14) translocation
- Chimeric fusion proteins MLL/AF10 and CALM/AF10 consistently retain the leucine zipper motif of MLLT10
- The leucine zipper interacts with GAS41, a protein previously identified as the product of an amplified gene in a glioblastoma
- GAS41 interacts with integrase interactor-1 (INI1), a component of the SWI/SNF complex, which acts to remodel chromatin and to modulate transcription
- Retention of the leucine zipper in the MLL and CALM fusions suggested that a key feature of these chimeric proteins may be their ability to interfere in normal gene regulation through interaction with the adenosine triphosphate-dependent chromatin remodeling complexes.
Compare Similar Items
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Antigen: MLLT10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MLLT10
Gene Alias: Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 361285, 8028
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P55197
Gene Symbols: MLLT10
Immunogen: Synthetic peptide sequence (RLEDTTARFTNAN) corresponding to the internal amino acids of MLLT10
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MLLT10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MLLT10
Gene Alias:
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
361285, 8028
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P55197
Gene Symbols:
MLLT10
Immunogen:
Synthetic peptide sequence (RLEDTTARFTNAN) corresponding to the internal amino acids of MLLT10
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GABRG2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gabrg2
Gene Alias: CAE2, ECA2, GABA(A) receptor subunit gamma-2, GABA(A) receptor, gamma 2, GABAA-R, GABRA2, Gabrg2, Gabrg-2, gamma2, gamma-aminobutyrate receptor type A gamma-2 subuni, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2, gamma-aminobutyric acid A receptor gamma 2, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid receptor subunit gamma-2, gamma-aminobutyric acid type A receptor gamma2 subunit, gamma-aminobutyric acid type A receptor subunit gamma2, GEFSP3, LOC553402 protein, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit gamma-2, si:ch211-145n14.1
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 14406, 2566, 29709
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P18507, P18508, P22723
Gene Symbols: Gabrg2
Immunogen: Synthetic peptide sequence (NNATHLQERDE) corresponding to the internal amino acids of GABRG2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GABRG2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gabrg2
Gene Alias:
CAE2, ECA2, GABA(A) receptor subunit gamma-2, GABA(A) receptor, gamma 2, GABAA-R, GABRA2, Gabrg2, Gabrg-2, gamma2, gamma-aminobutyrate receptor type A gamma-2 subuni, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2, gamma-aminobutyric acid A receptor gamma 2, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid receptor subunit gamma-2, gamma-aminobutyric acid type A receptor gamma2 subunit, gamma-aminobutyric acid type A receptor subunit gamma2, GEFSP3, LOC553402 protein, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit gamma-2, si:ch211-145n14.1
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
14406, 2566, 29709
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P18507, P18508, P22723
Gene Symbols:
Gabrg2
Immunogen:
Synthetic peptide sequence (NNATHLQERDE) corresponding to the internal amino acids of GABRG2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TTC8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TTC8
Gene Alias: 0610012F22Rik; AV001447; Bardet-Biedl syndrome 8 protein; Bardet-Biedl syndrome 8 protein homolog; Bardet-Biedl syndrome type 8; BBS8; RP51; tetratricopeptide repeat domain 8; tetratricopeptide repeat protein 8; TPR repeat protein 8; TTC8
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 123016
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8TAM2
Gene Symbols: TTC8
Immunogen: Synthetic peptide sequence (KEVLKQDNTHVE) corresponding to the internal amino acids of TTC8
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TTC8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TTC8
Gene Alias:
0610012F22Rik; AV001447; Bardet-Biedl syndrome 8 protein; Bardet-Biedl syndrome 8 protein homolog; Bardet-Biedl syndrome type 8; BBS8; RP51; tetratricopeptide repeat domain 8; tetratricopeptide repeat protein 8; TPR repeat protein 8; TTC8
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
123016
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8TAM2
Gene Symbols:
TTC8
Immunogen:
Synthetic peptide sequence (KEVLKQDNTHVE) corresponding to the internal amino acids of TTC8
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CXCR6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CXCR6
Gene Alias: BB217514; BONZO; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; chemokine receptor CXCR6; CXC; C-X-C chemokine receptor type 6; CXC motif chemokine; C-X-C motif chemokine receptor 6; Cxcr6; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998; STRL33; TYMSTR
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 10663
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: O00574
Gene Symbols: CXCR6
Immunogen: Synthetic peptide sequence (SEDNSKTFSASHN) corresponding to the C-terminus amino acids of CXCR6
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CXCR6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CXCR6
Gene Alias:
BB217514; BONZO; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; chemokine receptor CXCR6; CXC; C-X-C chemokine receptor type 6; CXC motif chemokine; C-X-C motif chemokine receptor 6; Cxcr6; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998; STRL33; TYMSTR
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
10663
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O00574
Gene Symbols:
CXCR6
Immunogen:
Synthetic peptide sequence (SEDNSKTFSASHN) corresponding to the C-terminus amino acids of CXCR6
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG