PIPA519892
DFFB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519892-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA519892 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
DFFB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DFFB
Gene Alias
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13368
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O54788
Gene Symbols
DFFB
Immunogen
A 16 amino acid peptide near the carboxy terminus of murine CAD
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Description
- In Western blot applications, this antibody detects a band at ∽40kDa
- A suggested positive control is mouse lung tissue lysate
- PA5-19892 can be used with blocking peptide PEP-0020
- Caspase-activated DNase (CAD) cleaves chromosomal DNA during apoptosis
- Apoptosis which is a cell death process removing toxic and/or useless cells during mammalian development can be induced by a variety of stimuli, including the death factors of the tumor necrosis factor family, or UV irradiation, anticancer drugs, and survival factor deprivation
- The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units
- CAD, which can be activated by caspases, exists as a complex with its inhibitor, inhibitor of CAD (ICAD)
- ICAD helps correct folding of CAD and remains complexed with CAD to inhibit the DNase activity of CAD
- Caspase, which is activated during the apoptotic process, cleaves ICAD, and the CAD released from ICAD enters the nuclei to cleave the chromosomal DNA
- Internal as well as external signals can activate caspases and this is under the control of the balance between pro-and anti-apoptotic proteins of the Bcl-2 family, heat shock proteins, and inhibitors of apoptosis proteins (IAPs)
- Currently, fourteen members of the caspase family have been identified, of which seven mediate apoptosis.
Compare Similar Items
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Antigen: DFFB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DFFB
Gene Alias: 2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13368
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O54788
Gene Symbols: DFFB
Immunogen: A 16 amino acid peptide near the carboxy terminus of murine CAD
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DFFB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DFFB
Gene Alias:
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13368
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O54788
Gene Symbols:
DFFB
Immunogen:
A 16 amino acid peptide near the carboxy terminus of murine CAD
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: APAF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APAF1
Gene Alias: 6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11783, 317, 78963
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O14727, O88879, Q9EPV5
Gene Symbols: APAF1
Immunogen: A peptide corresponding to amino acids near the amino terminus of human Apaf1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
APAF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APAF1
Gene Alias:
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11783, 317, 78963
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O14727, O88879, Q9EPV5
Gene Symbols:
APAF1
Immunogen:
A peptide corresponding to amino acids near the amino terminus of human Apaf1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: APAF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APAF1
Gene Alias: 6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11783, 317, 78963
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O14727, O88879, Q9EPV5
Gene Symbols: APAF1
Immunogen: A peptide corresponding to amino acids near the carboxy terminus of human Apaf1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
APAF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APAF1
Gene Alias:
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11783, 317, 78963
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O14727, O88879, Q9EPV5
Gene Symbols:
APAF1
Immunogen:
A peptide corresponding to amino acids near the carboxy terminus of human Apaf1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD264 (TRAIL-R4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNFRSF10D
Gene Alias: CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8793
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q9UBN6
Gene Symbols: TNFRSF10D
Immunogen: A 15 amino acid peptide near the center of human DcR2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD264 (TRAIL-R4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNFRSF10D
Gene Alias:
CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8793
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q9UBN6
Gene Symbols:
TNFRSF10D
Immunogen:
A 15 amino acid peptide near the center of human DcR2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG