PIPA519916

IKK beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA519916-Each-of-1 In Stock ₹ 44,705.10

PIPA519916 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IKK beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3551

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O14920

Gene Symbols

Ikbkb

Immunogen

A peptide corresponding to amino acids near the carboxy terminus of human IKK beta

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • In Western blot applications, this antibody detects a band at ∽87kDa
  • A suggested positive control is Jurkat cell lysate
  • PA5-19916 can be used with blocking peptide PEP-0042
  • Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Compare Similar Items

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Img

Thermo Scientific

PIPA519916

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Antigen:
IKK beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
A peptide corresponding to amino acids near the carboxy terminus of human IKK beta

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519920

--


Antigen:
IL-1RAcP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1RAP

Gene Alias:
6430709H04Rik; AI255955; AV239853; C3orf13; hide; IL 1R 3; IL 1R3; IL 1RAcP; IL 1RAP; IL-1 receptor accessory protein; IL1R3; IL-1R3; IL-1R-3; IL1RAcP; IL-1RAcp; Il1racpb; Il1rap; ILN; Interleukin; interleukin 1 receptor accessory protein; interleukin-1 receptor 3; Interleukin-1 receptor accessory protein; interleukin-1 receptor accessory protein beta; Interleukin-33 receptot beta chain

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3556

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9NPH3

Gene Symbols:
IL1RAP

Immunogen:
A peptide corresponding to amino acids 525 to 540 of human IL-1RAcP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519921

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Antigen:
IL-1RAcP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1RAP

Gene Alias:
6430709H04Rik; AI255955; AV239853; C3orf13; hide; IL 1R 3; IL 1R3; IL 1RAcP; IL 1RAP; IL-1 receptor accessory protein; IL1R3; IL-1R3; IL-1R-3; IL1RAcP; IL-1RAcp; Il1racpb; Il1rap; ILN; Interleukin; interleukin 1 receptor accessory protein; interleukin-1 receptor 3; Interleukin-1 receptor accessory protein; interleukin-1 receptor accessory protein beta; Interleukin-33 receptot beta chain

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3556

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9NPH3

Gene Symbols:
IL1RAP

Immunogen:
A peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519924

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Antigen:
DcR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF6B

Gene Alias:
DcR3; Decoy receptor 3; decoy receptor 3 variant 1; decoy receptor 3 variant 2; decoy receptor for Fas ligand; DJ583P15.1.1; hCG_2044836; M68; M68E; OTTHUMP00000031583; TNF receptor superfamily member 6b; TNFRSF6B; TR6; tumor necrosis factor receptor superfamily member 6B; tumor necrosis factor receptor superfamily member 6b, decoy; tumor necrosis factor receptor superfamily, member 6b, decoy; UNQ186/PRO212

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8771

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95407

Gene Symbols:
TNFRSF6B

Immunogen:
A peptide corresponding to amino acids near the amino terminus of human DcR3 precursor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG