PIPA519977

NOXA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519977-Each-of-1 In Stock ₹ 47,015.22

PIPA519977 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

NOXA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PMAIP1

Gene Alias

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

492821, 5366, 58801

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q13794, Q5U777, Q9JM54

Gene Symbols

PMAIP1

Immunogen

A synthetic peptide corresponding to 17 amino acids at the amino terminus of mouse Noxa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • A suggested positive control is human stomach tissue lysate
  • PA5-19977 can be used with blocking peptide PEP-0305
  • Apoptosis is related to many diseases and development
  • The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
  • A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
  • Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
  • X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
  • Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
  • Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
  • Noxa and PUMA may represent direct mediators of p53-induced apoptosis
  • Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

Compare Similar Items

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Img

Thermo Scientific

PIPA519977

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Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
492821, 5366, 58801

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q13794, Q5U777, Q9JM54

Gene Symbols:
PMAIP1

Immunogen:
A synthetic peptide corresponding to 17 amino acids at the amino terminus of mouse Noxa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519980

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Antigen:
PERP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PERP

Gene Alias:
1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64065

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q96FX8

Gene Symbols:
PERP

Immunogen:
A synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519981

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Antigen:
IL-21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL21

Gene Alias:
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
59067

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9HBE4

Gene Symbols:
IL21

Immunogen:
A synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519987

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Antigen:
IL-22 Receptor alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il22ra1

Gene Alias:
9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; cytokine receptor family 2 member 9; ENSMUSG00000073746; il-22 receptor; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; interleukin-22 receptor subunit alpha-1; RGD1559655; zcytoR11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362629, 58985

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8N6P7

Gene Symbols:
Il22ra1

Immunogen:
A synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG