PIPA520033

Caspase 12 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520033-Each-of-1 In Stock ₹ 44,705.10

PIPA520033 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Caspase 12

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CASP12

Gene Alias

CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100506742, 12364, 156117

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O08736, Q6UXS9, Q920D5

Gene Symbols

CASP12

Immunogen

A synthetic peptide corresponding to amino acids within the large cleavage product of murine caspase-12.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA575318

--

Img

Thermo Scientific

PIPA572888

--

Img

Thermo Scientific

PIPA596373

--

Img

Thermo Scientific

PIMA535194

--

Img

Thermo Scientific

PIPA536378

--

Img

Thermo Scientific

PIMA525714

--

Img

Thermo Scientific

PIMA535119

--

Img

Thermo Scientific

PIPA536421

--

Description

  • A suggested positive control is human heart tissue lysate
  • PA5-20033 can be used with blocking peptide PEP-0152
  • Three distinct signaling pathways lead to programmed cell death (apoptosis)
  • The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved
  • The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved
  • Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion
  • Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis
  • Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP)
  • Caspase-12 mediates cytotoxicity induced by amyloid-beta
  • Caspase-12 is ubiquitously expressed in mouse tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520033

--


Antigen:
Caspase 12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP12

Gene Alias:
CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506742, 12364, 156117

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O08736, Q6UXS9, Q920D5

Gene Symbols:
CASP12

Immunogen:
A synthetic peptide corresponding to amino acids within the large cleavage product of murine caspase-12.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520035

--


Antigen:
ALS2CR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STRADB

Gene Alias:
AA792893; Als2cr2; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; B830008M19; CALS-21; D1Ucla2; ILP-interacting protein; ILP-interacting protein homolog; ILP-interacting protein ILPIPA; ILPIP; ILPIPA; MGC102916; Papk; polyploidy associated protein kinase; polyploidy associated protein kinase PAPK-A; polyploidy-associated protein kinase; PRO1038; pseudokinase ALS2CR2; RGD1559449; STE20 related adaptor beta; STE20-related kinase adapter protein beta; STE20-related kinase adaptor beta; STRAD beta; Stradb; Syradb

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
227154, 501146, 55437

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8K4T3, Q9C0K7

Gene Symbols:
STRADB

Immunogen:
A synthetic peptide corresponding to amino acids near the center of human ILPIP.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520039

--


Antigen:
ACE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACE2

Gene Alias:
2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
59272, 70008

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8R0I0, Q9BYF1

Gene Symbols:
ACE2

Immunogen:
A synthetic peptide corresponding to amino acids near the center of human ACE2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520040

--


Antigen:
ACE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACE2

Gene Alias:
2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302668, 59272, 70008

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5EGZ1, Q8R0I0, Q9BYF1

Gene Symbols:
ACE2

Immunogen:
A synthetic peptide corresponding to amino acids near the C-terminus of human ACE2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG