PIPA520080

UBC13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520080-Each-of-1 In Stock ₹ 50,309.28

PIPA520080 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

UBC13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBE2N

Gene Alias

1500026J17Rik; AL022654; BB101821; bendless protein; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; Blu; E2 ubiquitin-conjugating enzyme N; epididymis secretory protein Li 71; HEL-S-71; MGC131857; MGC8489; UBC13; UbcH13; UbcH-ben; UBCHBEN; UBC13; UBE2N; Ubiquitin carrier protein N; ubiquitin conjugating enzyme E2 N; ubiquitin conjugating enzyme E2N; ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N; ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-protein ligase N; yeast UBC13 homolog

Host Species

Rabbit

Purification Method

Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116725, 7334, 93765

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P61088, P61089, Q9EQX9

Gene Symbols

UBE2N

Immunogen

A peptide corresponding to 15 amino acids near the C-terminus of human UBC13.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Novus Biologicals

NB318800

--

Img

Novus Biologicals

NB274748A48

--

Img

Novus Biologicals

NB318762

--

Img

Novus Biologicals

NB318773

--

Img

Novus Biologicals

NB318766

--

Img

Novus Biologicals

NB274737APC

--

Img

Novus Biologicals

NB324224

--

Img

Novus Biologicals

NB395719

--

Description

  • A suggested positive control is human small intestine tissue lysate
  • PA5-20080 can be used with blocking peptide PEP-0198
  • The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains
  • This type of polyubiquitination does not lead to protein degradation by the proteasome
  • Mediates transcriptional activation of target genes
  • Plays a role in the control of progress through the cell cycle and differentiation
  • Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage
  • Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair
  • Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD
  • Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes
  • Together with RNF135 and UB2V1, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIG-I/DDX58 to activate the downstream signaling pathway that leads to interferon beta production
  • UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway
  • (Uniprot)

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520080

--


Antigen:
UBC13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBE2N

Gene Alias:
1500026J17Rik; AL022654; BB101821; bendless protein; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; Blu; E2 ubiquitin-conjugating enzyme N; epididymis secretory protein Li 71; HEL-S-71; MGC131857; MGC8489; UBC13; UbcH13; UbcH-ben; UBCHBEN; UBC13; UBE2N; Ubiquitin carrier protein N; ubiquitin conjugating enzyme E2 N; ubiquitin conjugating enzyme E2N; ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N; ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-protein ligase N; yeast UBC13 homolog

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116725, 7334, 93765

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P61088, P61089, Q9EQX9

Gene Symbols:
UBE2N

Immunogen:
A peptide corresponding to 15 amino acids near the C-terminus of human UBC13.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520081

--


Antigen:
UBE2V1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ube2v1

Gene Alias:
0610011J09Rik; AI256840; CIR1; CROC1; CROC-1; CROC1B; CROC-1B; CROC-1UBE2V; D7Bwg1382e; DJ1185N5.1.3; DNA-binding protein; KUA-UEV; P/OKcl.19; TRAF6-regulated IKK activator 1 beta Uev1A; UBE2V; Ube2v1; ubiquitin conjugating enzyme E2 V1; ubiquitin conjugating enzyme E2 variant 1; ubiquitin-conjugating enzyme E2 variant 1; UEV1; UEV-1; UEV1A; UEV-1CIR1

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296390, 66589, 7335

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q13404, Q9CZY3

Gene Symbols:
Ube2v1

Immunogen:
A peptide corresponding to 15 amino acids near the C-terminus of human UEV1A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520083

--


Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 313121, 6885

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O43318, P0C8E4, Q62073

Gene Symbols:
MAP3K7

Immunogen:
A synthetic peptide corresponding to 14 amino acids near the amino-terminus of human TAK1 isoform a.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520084

--


Antigen:
TAB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TAB1

Gene Alias:
2310012M03Rik; 3'-Tab1; b2b449Clo; beta activated kinase-1 binding protein-1; MAP3K7IP1; MGC57664; mitogen activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; RP3-407F17.2; TAB1; TAB1beta; TAK1-binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10454, 66513

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q15750, Q8CF89

Gene Symbols:
TAB1

Immunogen:
A synthetic peptide corresponding to 13 amino acids in the center of human TAB1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG