PIPA520086
IRF3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520086-Each-of-1 | In Stock | ₹ 47,870.82 |
PIPA520086 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,870.82
GST (18%): ₹ 8,616.748
Total Price: ₹ 56,487.568
Antigen
IRF3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3661, 54131
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P70671, Q14653
Gene Symbols
IRF3
Immunogen
A peptide corresponding to 14 amino acids near the carboxy terminus of human IRF3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is Ramos cell lysate
- PA5-20086 can be used with blocking peptide PEP-0204
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
Compare Similar Items
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Antigen: IRF3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3661, 54131
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P70671, Q14653
Gene Symbols: IRF3
Immunogen: A peptide corresponding to 14 amino acids near the carboxy terminus of human IRF3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
IRF3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3661, 54131
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P70671, Q14653
Gene Symbols:
IRF3
Immunogen:
A peptide corresponding to 14 amino acids near the carboxy terminus of human IRF3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: IRF3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3661
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: A peptide corresponding to 14 amino acids near the center of human IRF3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IRF3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3661
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
A peptide corresponding to 14 amino acids near the center of human IRF3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IRF8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Irf8
Gene Alias: AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15900, 292060, 3394
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P23611, Q02556
Gene Symbols: Irf8
Immunogen: A peptide corresponding to 16 amino acids near the carboxy terminus of human IRF8.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IRF8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Irf8
Gene Alias:
AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15900, 292060, 3394
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P23611, Q02556
Gene Symbols:
Irf8
Immunogen:
A peptide corresponding to 16 amino acids near the carboxy terminus of human IRF8.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Avian Influenza HA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: Avian Hemagglutinin; flu hemagglutinin; influenza a; Influenza HA; influenza hemagglutinin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: A synthetic peptide corresponding to 15 amino acids at the amino terminus of the avian influenza hemagglutinin protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
Avian Influenza HA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Avian Hemagglutinin; flu hemagglutinin; influenza a; Influenza HA; influenza hemagglutinin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
A synthetic peptide corresponding to 15 amino acids at the amino terminus of the avian influenza hemagglutinin protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG