PIPA520137

IRS1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA520137-Each-of-1 In Stock ₹ 44,705.10

PIPA520137 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IRS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRS1

Gene Alias

G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16367, 3667

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P35568, P35569

Gene Symbols

IRS1

Immunogen

A 16 amino acid peptide from near the center of human IRS-1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • A suggested positive control is PC-3 cell lysate
  • PA5-20137 can be used with blocking peptide PEP-0344
  • IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
  • IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
  • An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
  • Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
  • Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
  • IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.

Compare Similar Items

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Img

Thermo Scientific

PIPA520137

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Antigen:
IRS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 3667

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P35568, P35569

Gene Symbols:
IRS1

Immunogen:
A 16 amino acid peptide from near the center of human IRS-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520146

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Antigen:
CTRP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1QTNF1

Gene Alias:
1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1qtnf1; Complement C1q tumor necrosis factor-related protein 1; Ctrp1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114897, 303701, 56745

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5XIG2, Q9BXJ1, Q9QXP7

Gene Symbols:
C1QTNF1

Immunogen:
A 15 amino acid peptide from near the amino-terminus of human CTRP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520148

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Antigen:
CTRP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1QTNF2

Gene Alias:
1810033K05Rik; C1q and tumor necrosis factor related protein 2; C1qtnf2; Complement C1q tumor necrosis factor-related protein 2; complement-c1q tumor necrosis factor-related protein 2; Crtp2; CTRP2; mCTRP2; RGD1561041; UNQ6349/PRO21054; zacrp2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114898, 69183

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9BXJ5, Q9D8U4

Gene Symbols:
C1QTNF2

Immunogen:
A 16 amino acid peptide from near the amino-terminus of human CTRP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520149

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Antigen:
CTRP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1qtnf3

Gene Alias:
2310005P21Rik; C1ATNF3; C1q and tumor necrosis factor related protein 3; C1qtnf3; cartducin; cartonectin; collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; complement C1q tumor necrosis factor-related protein 3; Corcs; CORS; CORS26; CORS-26; CTRP3; Secretory protein CORS26; UNQ753/PRO1484

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114899, 81799

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9BXJ4, Q9ES30

Gene Symbols:
C1qtnf3

Immunogen:
A 16 amino acid peptide from near the center of human CTRP3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG