PIPA520161

GITRL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520161-Each-of-1 In Stock ₹ 47,271.90

PIPA520161 - Each of 1

₹ 47,271.90

In Stock

Quantity

1

Base Price: ₹ 47,271.90

GST (18%): ₹ 8,508.942

Total Price: ₹ 55,780.842

Antigen

GITRL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFSF18

Gene Alias

Activation-inducible TNF-related ligand; AITR ligand; AITRL; GITR ligand; Gitrl; GITRLigand; Glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand; hGITRL; RP1-15D23.1; TL6; TNF superfamily member 18; Tnfsf18; TNLG2A; tumor necrosis factor (ligand) superfamily member 18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18; UNQ149/PRO175

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

240873, 8995

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q7TS55, Q9UNG2

Gene Symbols

TNFSF18

Immunogen

purified recombinant human GITR ligand.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • A suggested positive control is THP-1 cell lysate
  • The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappa-B and various mitogen-activated protein kinases
  • The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions
  • Its ligand GITRL is expressed in endothelial and antigen-presenting cells and can activate NF-kappa-B, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR
  • Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappa-B activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2.

Compare Similar Items

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Img

Thermo Scientific

PIPA520161

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Antigen:
GITRL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFSF18

Gene Alias:
Activation-inducible TNF-related ligand; AITR ligand; AITRL; GITR ligand; Gitrl; GITRLigand; Glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand; hGITRL; RP1-15D23.1; TL6; TNF superfamily member 18; Tnfsf18; TNLG2A; tumor necrosis factor (ligand) superfamily member 18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18; UNQ149/PRO175

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
240873, 8995

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q7TS55, Q9UNG2

Gene Symbols:
TNFSF18

Immunogen:
purified recombinant human GITR ligand.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520162

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Antigen:
NGFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ngfr

Gene Alias:
CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18053, 4804

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P08138, Q9Z0W1

Gene Symbols:
Ngfr

Immunogen:
purified recombinant human NGFR.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520165

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Antigen:
TRAF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF3

Gene Alias:
AI528849; amn; CAP1; CAP-1; CD40 associated protein 1; CD40 binding protein; CD40 receptor associated factor 1; CD40 receptor-associated factor 1; CD40-binding protein; CD40BP; CRAF1; IIAE5; LAP1; LMP1-associated protein 1; RING-type E3 ubiquitin transferase TRAF3; T-BAM; TNF receptor associated factor 3; Tnf receptor-associated factor 3; TRAF3; Trafamn

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22031, 7187

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q13114, Q60803

Gene Symbols:
TRAF3

Immunogen:
A 16 amino acid peptide from near the carboxy terminus of human TRAF3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520168

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Antigen:
Bit1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptrh2

Gene Alias:
A230072I16Rik; Bcl-2 inhibitor of transcription; bcl-2 inhibitor of transcription 1; BIT1; CFAP37; CGI-147; cilia and flagella associated protein 37; IMNEPD; OTTHUMP00000205936; peptidyl-tRNA hydrolase 2; peptidyl-tRNA hydrolase 2, mitochondrial; PTH; PTH 2; Pth2; Ptrh2; RGD1306819

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
217057, 51651

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8R2Y8, Q9Y3E5

Gene Symbols:
Ptrh2

Immunogen:
A 16 amino acid peptide from near the center of human Bit1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG