PIPA520257
TRPC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520257-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA520257 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TRPC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Trpc6
Gene Alias
AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22068, 7225
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q61143, Q9Y210
Gene Symbols
Trpc6
Immunogen
A 14 amino acid peptide from near the amino terminus of human TRPC6.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is K562 cell lysate
- PA5-20257 can be used with blocking peptide PEP-0393
- Trpc6 forms a receptor-activated calcium channel in the cell membrane
- The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
- Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
- Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
- Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "ecanonical TRP"e (TRPC) family
- The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
- Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
- When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
- Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
- There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
- Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.
Compare Similar Items
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Antigen: TRPC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Trpc6
Gene Alias: AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22068, 7225
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q61143, Q9Y210
Gene Symbols: Trpc6
Immunogen: A 14 amino acid peptide from near the amino terminus of human TRPC6.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TRPC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Trpc6
Gene Alias:
AV025995; bZ1P14.9; calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; short transient receptor potential channel 6; short transient receptor potential channel 6a; si:rp71-1p14.9; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel subfamily c member 6a; transient receptor potential cation channel TRPC6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 6a; transient receptor potential channel 6; transient receptor potential channel subfamily C member 6; transient receptor protein 6; TRP6; TRP-6; trp6A; TRPC6; trpc6a; Trrp6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22068, 7225
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q61143, Q9Y210
Gene Symbols:
Trpc6
Immunogen:
A 14 amino acid peptide from near the amino terminus of human TRPC6.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Cyclin O
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCNO
Gene Alias: C86987; CCNO; Ccnu; CILD29; cyclin domain containing; cyclin O; cyclin U; cyclin-like uracil-DNA glycosylase; cyclin-O; E130318K11; RGD1565217; UDG2; Ung2; uracil DNA glycosylase 2; uracil-DNA glycosylase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10309, 218630, 499528
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P0C242, P22674
Gene Symbols: CCNO
Immunogen: A 14 amino acid synthetic peptide from near the amino terminus of human Cyclin O
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cyclin O
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCNO
Gene Alias:
C86987; CCNO; Ccnu; CILD29; cyclin domain containing; cyclin O; cyclin U; cyclin-like uracil-DNA glycosylase; cyclin-O; E130318K11; RGD1565217; UDG2; Ung2; uracil DNA glycosylase 2; uracil-DNA glycosylase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10309, 218630, 499528
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P0C242, P22674
Gene Symbols:
CCNO
Immunogen:
A 14 amino acid synthetic peptide from near the amino terminus of human Cyclin O
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cyclin O
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCNO
Gene Alias: C86987; CCNO; Ccnu; CILD29; cyclin domain containing; cyclin O; cyclin U; cyclin-like uracil-DNA glycosylase; cyclin-O; E130318K11; RGD1565217; UDG2; Ung2; uracil DNA glycosylase 2; uracil-DNA glycosylase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10309, 218630, 499528
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P0C242, P22674
Gene Symbols: CCNO
Immunogen: a 13 amino acid synthetic peptide from near the center of human Cyclin O
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cyclin O
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCNO
Gene Alias:
C86987; CCNO; Ccnu; CILD29; cyclin domain containing; cyclin O; cyclin U; cyclin-like uracil-DNA glycosylase; cyclin-O; E130318K11; RGD1565217; UDG2; Ung2; uracil DNA glycosylase 2; uracil-DNA glycosylase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10309, 218630, 499528
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P0C242, P22674
Gene Symbols:
CCNO
Immunogen:
a 13 amino acid synthetic peptide from near the center of human Cyclin O
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BAG1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bag1
Gene Alias: BAG family molecular chaperone regulator 1; Bag1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; bcl-2-associated athanogene 1; BCL2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; Rap46; receptor-associated protein, 46-KD; RP11-326F20.2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12017, 297994, 573
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: B0K019, Q60739, Q99933
Gene Symbols: Bag1
Immunogen: A 14 amino acid peptide from near the carboxy terminus of human BAG-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BAG1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bag1
Gene Alias:
BAG family molecular chaperone regulator 1; Bag1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; bcl-2-associated athanogene 1; BCL2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; Rap46; receptor-associated protein, 46-KD; RP11-326F20.2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12017, 297994, 573
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
B0K019, Q60739, Q99933
Gene Symbols:
Bag1
Immunogen:
A 14 amino acid peptide from near the carboxy terminus of human BAG-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG