PIPA520276

RIG-I Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520276-Each-of-1 In Stock ₹ 47,699.70

PIPA520276 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

RIG-I

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species

Rabbit

Purification Method

Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

230073, 23586, 297989

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O95786, Q6Q899

Gene Symbols

DDX58

Immunogen

human GST-tagged RIG-1 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • A suggested positive control is C2C12 cell lysate
  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

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Img

Thermo Scientific

PIPA520276

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Antigen:
RIG-I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230073, 23586, 297989

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95786, Q6Q899

Gene Symbols:
DDX58

Immunogen:
human GST-tagged RIG-1 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520277

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Antigen:
Cullin 9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL9

Gene Alias:
1810035I07Rik; CUL9; CUL-9; cullin 9; cullin-9; H7AP1; KIAA0708; mKIAA0708; p53-associated parkin-like cytoplasmic protein; PARC; parkin-like cytoplasmic p53 binding protein; RP3-330M21.2; UbcH7-associated protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23113, 78309

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80TT8, Q8IWT3

Gene Symbols:
CUL9

Immunogen:
A 17 amino acid peptide from near the carboxy terminus of human PARC.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520279

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Antigen:
SHP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN11

Gene Alias:
2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19247, 25622, 5781

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P35235, P41499, Q06124

Gene Symbols:
PTPN11

Immunogen:
A 14 amino acid peptide from near the amino terminus of human SHP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520280

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Antigen:
IRF7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF7

Gene Alias:
IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
293624, 3665, 54123

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P70434, Q92985

Gene Symbols:
IRF7

Immunogen:
A peptide corresponding to 14 amino acids near the carboxy terminus of human IRF7.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG