PIPA520330
Nephrin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520330-Each-of-1 | In Stock | ₹ 47,528.58 |
PIPA520330 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,528.58
GST (18%): ₹ 8,555.144
Total Price: ₹ 56,083.724
Antigen
Nephrin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Nphs1
Gene Alias
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4868, 54631, 64563
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O60500, Q9QZS7, Q9R044
Gene Symbols
Nphs1
Immunogen
A 14 amino acid peptide from near the carboxy terminus of human Nephrin.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Despite its predicted molecular weight, Nephrin often migrates at a lower molecular weight in SDS-PAGE
- A suggested positive control is mouse kidney tissue lysate
- PA5-20330 can be used with blocking peptide PEP-0450
- Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
- Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
- Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
- Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
- Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
- Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
- Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
- The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
- Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.
Compare Similar Items
Show Difference
Antigen: Nephrin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nphs1
Gene Alias: CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4868, 54631, 64563
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O60500, Q9QZS7, Q9R044
Gene Symbols: Nphs1
Immunogen: A 14 amino acid peptide from near the carboxy terminus of human Nephrin.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nephrin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nphs1
Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4868, 54631, 64563
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O60500, Q9QZS7, Q9R044
Gene Symbols:
Nphs1
Immunogen:
A 14 amino acid peptide from near the carboxy terminus of human Nephrin.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TRBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TARBP1
Gene Alias: Gm17296; Gm179; predicted gene, 17296; probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; Tarbp1; TRM3; tRNA methyltransferase 3 homolog; TRP185; TRP-185
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 212728, 6894
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q13395
Gene Symbols: TARBP1
Immunogen: A 17 amino acid peptide from near the center of human TRBP1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TRBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TARBP1
Gene Alias:
Gm17296; Gm179; predicted gene, 17296; probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; Tarbp1; TRM3; tRNA methyltransferase 3 homolog; TRP185; TRP-185
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
212728, 6894
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q13395
Gene Symbols:
TARBP1
Immunogen:
A 17 amino acid peptide from near the center of human TRBP1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MDA5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IFIH1
Gene Alias: 9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64135
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q9BYX4
Gene Symbols: IFIH1
Immunogen: A 16 amino acid peptide from near the carboxy terminus of human MDA5.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MDA5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IFIH1
Gene Alias:
9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64135
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q9BYX4
Gene Symbols:
IFIH1
Immunogen:
A 16 amino acid peptide from near the carboxy terminus of human MDA5.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MDA5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IFIH1
Gene Alias: 9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64135, 71586
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q8R5F7, Q9BYX4
Gene Symbols: IFIH1
Immunogen: A 16 amino acid peptide from near the center of human MDA5.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MDA5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IFIH1
Gene Alias:
9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64135, 71586
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q8R5F7, Q9BYX4
Gene Symbols:
IFIH1
Immunogen:
A 16 amino acid peptide from near the center of human MDA5.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG