PIPA520417
PTEN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520417-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA520417 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PTEN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTEN
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19211, 5728
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O08586, P60484
Gene Symbols
PTEN
Immunogen
A 16 amino acid peptide from near the carboxy terminus of human PTEN.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- A suggested positive control is PC-3 cell lysate
- PA5-20417 can be used with blocking peptide PEP-0534
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
Compare Similar Items
Show Difference
Antigen: PTEN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A 16 amino acid peptide from near the carboxy terminus of human PTEN.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PTEN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A 16 amino acid peptide from near the carboxy terminus of human PTEN.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: LIS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PAFAH1B1
Gene Alias: HAMAP-Rule:MF_03141}; Lis1; Lis-1; LIS-1 {ECO:0000255; LIS2; lissencephaly 1 protein; lissencephaly-1 protein; lissencephaly-1 protein {ECO:0000255; MDCR; MDS; Mdsh; MGC25297; Miller-Dieker syndrome chromosome region; MMS10-U; Ms10u; NudF; PAF acetylhydrolase 45 kDa subunit; PAF acetylhydrolase 45 kDa subunit {ECO:0000255; PAFAH; PAF-AH 45 kDa subunit; PAF-AH 45 kDa subunit {ECO:0000255; PAFAH alpha; PAF-AH alpha; PAFAH alpha {ECO:0000255; PAF-AH alpha {ECO:0000255; PAF-AH beta; Pafah1b1; Pafaha; platelet activating factor acetylhydrolase 1b regulatory subunit 1; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform variant; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255; platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); RP23-194P5.2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18472, 5048, 83572
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P43034, P63004, P63005
Gene Symbols: PAFAH1B1
Immunogen: A 14 amino acid peptide from near the carboxy terminus of human LIS1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LIS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PAFAH1B1
Gene Alias:
HAMAP-Rule:MF_03141}; Lis1; Lis-1; LIS-1 {ECO:0000255; LIS2; lissencephaly 1 protein; lissencephaly-1 protein; lissencephaly-1 protein {ECO:0000255; MDCR; MDS; Mdsh; MGC25297; Miller-Dieker syndrome chromosome region; MMS10-U; Ms10u; NudF; PAF acetylhydrolase 45 kDa subunit; PAF acetylhydrolase 45 kDa subunit {ECO:0000255; PAFAH; PAF-AH 45 kDa subunit; PAF-AH 45 kDa subunit {ECO:0000255; PAFAH alpha; PAF-AH alpha; PAFAH alpha {ECO:0000255; PAF-AH alpha {ECO:0000255; PAF-AH beta; Pafah1b1; Pafaha; platelet activating factor acetylhydrolase 1b regulatory subunit 1; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform variant; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255; platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); RP23-194P5.2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18472, 5048, 83572
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P43034, P63004, P63005
Gene Symbols:
PAFAH1B1
Immunogen:
A 14 amino acid peptide from near the carboxy terminus of human LIS1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Kinesin 5A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KIF5A
Gene Alias: D10Bwg0738e; D12S1889; Khc; Kiaa4086; Kif5; Kif5a; kif5a {ECO:0000312; KIF5A variant protein; kinesin family member 5A; kinesin heavy chain isoform 5A; kinesin heavy chain isoform 5A; kinesin heavy chain; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; Kns; mKIAA4086; MY050; Neuronal kinesin heavy chain; NKHC; Nkhc1; RGD:1303035}; SPG10
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16572, 314906, 3798
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P33175, Q12840, Q6QLM7
Gene Symbols: KIF5A
Immunogen: A 20 amino acid peptide from near the carboxy terminus of human KIF5.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Kinesin 5A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KIF5A
Gene Alias:
D10Bwg0738e; D12S1889; Khc; Kiaa4086; Kif5; Kif5a; kif5a {ECO:0000312; KIF5A variant protein; kinesin family member 5A; kinesin heavy chain isoform 5A; kinesin heavy chain isoform 5A; kinesin heavy chain; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; Kns; mKIAA4086; MY050; Neuronal kinesin heavy chain; NKHC; Nkhc1; RGD:1303035}; SPG10
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16572, 314906, 3798
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P33175, Q12840, Q6QLM7
Gene Symbols:
KIF5A
Immunogen:
A 20 amino acid peptide from near the carboxy terminus of human KIF5.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Kinesin 5A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KIF5A
Gene Alias: D10Bwg0738e; D12S1889; Khc; Kiaa4086; Kif5; Kif5a; kif5a {ECO:0000312; KIF5A variant protein; kinesin family member 5A; kinesin heavy chain isoform 5A; kinesin heavy chain isoform 5A; kinesin heavy chain; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; Kns; mKIAA4086; MY050; Neuronal kinesin heavy chain; NKHC; Nkhc1; RGD:1303035}; SPG10
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16572, 314906, 3798
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P33175, Q12840, Q6QLM7
Gene Symbols: KIF5A
Immunogen: A 20 amino acid peptide from near the center of human KIF5.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Kinesin 5A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KIF5A
Gene Alias:
D10Bwg0738e; D12S1889; Khc; Kiaa4086; Kif5; Kif5a; kif5a {ECO:0000312; KIF5A variant protein; kinesin family member 5A; kinesin heavy chain isoform 5A; kinesin heavy chain isoform 5A; kinesin heavy chain; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; Kns; mKIAA4086; MY050; Neuronal kinesin heavy chain; NKHC; Nkhc1; RGD:1303035}; SPG10
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16572, 314906, 3798
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P33175, Q12840, Q6QLM7
Gene Symbols:
KIF5A
Immunogen:
A 20 amino acid peptide from near the center of human KIF5.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG