PIPA520539

COPS8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520539-Each-of-1 In Stock ₹ 44,705.10

PIPA520539 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

COPS8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cops8

Gene Alias

9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; Csn8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

108679, 10920, 363283

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q6P4Z9, Q8VBV7, Q99627

Gene Symbols

Cops8

Immunogen

A 15 amino acid peptide near the carboxy terminus of the human CSN8.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human liver tissue lysate
  • PA5-20539 can be used with blocking peptide PEP-0659
  • COPS8 is a COP9 signalosome (CSN), which is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome
  • The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes such as SCF, CSA or DDB2
  • It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases
  • CSN8 encodes the smallest and the least conserved but first identified subunit of CSN
  • Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

Compare Similar Items

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Img

Thermo Scientific

PIPA520539

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Antigen:
COPS8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cops8

Gene Alias:
9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; Csn8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108679, 10920, 363283

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6P4Z9, Q8VBV7, Q99627

Gene Symbols:
Cops8

Immunogen:
A 15 amino acid peptide near the carboxy terminus of the human CSN8.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520543

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Antigen:
SLC22A17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC22A17

Gene Alias:
1700094C23Rik; 24p3 receptor; 24p3R; AU041908; AW555662; BOCT; Boit; brain-specific organic ion transporter; brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; mBOCT; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; organic cation transporter BOCT; potent brain type organic ion transporter; rBOCT; SLC22A17; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17; solute carrier family 22, member 17

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
305886, 51310, 59049

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8WUG5, Q9D9E0, Q9P290

Gene Symbols:
SLC22A17

Immunogen:
A 14 amino acid peptide near the carboxy terminus of the human Slc22A17.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520544

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Antigen:
LIMP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCARB2

Gene Alias:
85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AMRF; CD 36; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 2; CD36 molecule; Cd36l2; EPM4; HLGP85; I79_021583; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; Lysosome membrane protein 2; lysosome membrane protein II; MLGP85; Scarb2; Scavenger receptor class B member 2; scavenger receptor class B, member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2; SR-BII

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12492, 950

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35114, Q14108

Gene Symbols:
SCARB2

Immunogen:
An 18 amino acid peptide from near the carboxy terminus of human LIMP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520547

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Antigen:
GRTP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRTP1

Gene Alias:
5430401C05Rik; C81211; GH regulated TBC protein 1; growth hormone regulated TBC protein 1; growth hormone-regulated TBC protein 1; Grtp1; LRRGT00052; RP11-391H12.7; TBC1 domain family member 6; Tbc1d6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361180, 66790, 79774

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q4QQU7, Q5TC63, Q9D3N8

Gene Symbols:
GRTP1

Immunogen:
An 18 amino acid peptide from near the amino terminus of human GRTP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG