PIPA520665

TREX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520665-Each-of-1 In Stock ₹ 47,186.34

PIPA520665 - Each of 1

₹ 47,186.34

In Stock

Quantity

1

Base Price: ₹ 47,186.34

GST (18%): ₹ 8,493.541

Total Price: ₹ 55,679.881

Antigen

TREX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TREX1

Gene Alias

1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100049583, 11277, 22040

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q91XB0, Q9NSU2

Gene Symbols

TREX1

Immunogen

A 15 amino acid peptide near the center of human TREX1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA520529

--

Img

Thermo Scientific

PIPA520480

--

Img

Thermo Scientific

PIPA536194

--

Img

Thermo Scientific

PIPA558431

--

Img

Thermo Scientific

PIPA575412

--

Img

Thermo Scientific

PIPA572819

--

Img

Thermo Scientific

PIPA520530

--

Img

Thermo Scientific

PIPA578173

--

Description

  • A suggested positive control is human spleen tissue lysate
  • PA5-20665 can be used with blocking peptide PEP-0785
  • Trex1 (ATRIP) is the major human 3' to 5' exonuclease which is required for checkpoint signaling after DNA damage
  • It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress
  • Trex1 is required for ATR expression
  • This gene uses two different open reading frames
  • The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint
  • The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human DNA polymerase III
  • Multiple transcript variants encoding different isoforms have been found
  • Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520665

--


Antigen:
TREX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX1

Gene Alias:
1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100049583, 11277, 22040

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q91XB0, Q9NSU2

Gene Symbols:
TREX1

Immunogen:
A 15 amino acid peptide near the center of human TREX1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520666

--


Antigen:
TREX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX2

Gene Alias:
3'-5' exonuclease TREX2; 3'-5' exonuclease TREX2 long form; RGD1562245; Three prime repair exonuclease 2; Trex2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11219, 24102, 309275

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9BQ50, Q9R1A9

Gene Symbols:
TREX2

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human TREX2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520670

--


Antigen:
IL-16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL16

Gene Alias:
FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116996, 16170, 3603

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O54824, Q14005

Gene Symbols:
IL16

Immunogen:
A 20 amino acid peptide near the amino terminus of human IL-16.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520671

--


Antigen:
IL-16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL16

Gene Alias:
FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116996, 16170, 3603

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O54824, Q14005

Gene Symbols:
IL16

Immunogen:
A 14 amino acid peptide near the amino terminus of human IL-16.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG