PIPA520759
MC4R Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520759-Each-of-1 | In Stock | ₹ 47,443.02 |
PIPA520759 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,443.02
GST (18%): ₹ 8,539.744
Total Price: ₹ 55,982.764
Antigen
MC4R
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MC4R
Gene Alias
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17202, 25635, 4160
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P32245, P56450, P70596
Gene Symbols
MC4R
Immunogen
A 19 amino acid peptide near the amino terminus of human MC4R.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is rat brain tissue lysate
- PA5-20759 can be used with blocking peptide PEP-0873
- Expression of MC4R has been reported in brain
- Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
- G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
- All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
- An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
- Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
- This "eturn-off"e activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
- Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.
Compare Similar Items
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Antigen: MC4R
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MC4R
Gene Alias: MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17202, 25635, 4160
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P32245, P56450, P70596
Gene Symbols: MC4R
Immunogen: A 19 amino acid peptide near the amino terminus of human MC4R.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MC4R
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MC4R
Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17202, 25635, 4160
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P32245, P56450, P70596
Gene Symbols:
MC4R
Immunogen:
A 19 amino acid peptide near the amino terminus of human MC4R.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RGS21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RGS21
Gene Alias: EG624910; regulator of G-protein signaling 21; regulator of G-protein signalling 21; RGS21
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 431704
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q2M5E4
Gene Symbols: RGS21
Immunogen: A 16 amino acid peptide near the center of human RGS21.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RGS21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RGS21
Gene Alias:
EG624910; regulator of G-protein signaling 21; regulator of G-protein signalling 21; RGS21
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
431704
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q2M5E4
Gene Symbols:
RGS21
Immunogen:
A 16 amino acid peptide near the center of human RGS21.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Fibulin 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EFEMP1
Gene Alias: DHRD; DRAD; EFEMP1; EGF containing fibulin like extracellular matrix protein 1; EGF containing fibulin-like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1; epidermal growth factor-containing fibulin-like extracellular matrix protein 1; extracellular protein S1-5; FBLN3; FBNL; FIBL-3; Fibrillin-like protein; Fibulin-3; FLJ35535; MGC111353; MLVT; MTLV; S1-5; T16
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2202
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q12805
Gene Symbols: EFEMP1
Immunogen: A 19 amino acid peptide near the carboxy terminus of human Fibulin 3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Fibulin 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EFEMP1
Gene Alias:
DHRD; DRAD; EFEMP1; EGF containing fibulin like extracellular matrix protein 1; EGF containing fibulin-like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1; epidermal growth factor-containing fibulin-like extracellular matrix protein 1; extracellular protein S1-5; FBLN3; FBNL; FIBL-3; Fibrillin-like protein; Fibulin-3; FLJ35535; MGC111353; MLVT; MTLV; S1-5; T16
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2202
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q12805
Gene Symbols:
EFEMP1
Immunogen:
A 19 amino acid peptide near the carboxy terminus of human Fibulin 3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SHOC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shoc2
Gene Alias: AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 309548, 56392, 8036
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O88520, Q6AYI5, Q9UQ13
Gene Symbols: Shoc2
Immunogen: A 21 amino acid peptide near the amino terminus of human SHOC2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHOC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Shoc2
Gene Alias:
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
309548, 56392, 8036
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O88520, Q6AYI5, Q9UQ13
Gene Symbols:
Shoc2
Immunogen:
A 21 amino acid peptide near the amino terminus of human SHOC2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG