PIPA521139

SIK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521139-Each-of-1 In Stock ₹ 44,277.30

PIPA521139 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

SIK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIK1

Gene Alias

EIEE30; HRT-20; Kid2; MSK; Myocardial SNF1-like kinase; Probable serine/threonine protein kinase SNF1LK (HRT-20) (Myocardial SNF1-like kinase); protein kinase KID2; salt inducible kinase 1; salt-inducible kinase 1; salt-inducible protein kinase 1; serine/threonine protein kinase; serine/threonine-protein kinase SIK1; Serine/threonine-protein kinase SNF1-like kinase 1; serine/threonine-protein kinase SNF1LK; SIK; Sik1; SIK-1; SNF1-like kinase; SNF1LK

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

150094

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P57059

Gene Symbols

SIK1

Immunogen

An 18 amino acid peptide near the center of human SIK1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA520811

--

Img

Thermo Scientific

PIPA521147

--

Img

Thermo Scientific

PIPA526629

--

Img

Thermo Scientific

PIPA520848

--

Img

Thermo Scientific

PIPA520849

--

Img

Thermo Scientific

PIPA520875

--

Img

Thermo Scientific

PIPA527484

--

Img

Thermo Scientific

PIPA521124

--

Description

  • A suggested positive control is human small intestine tissue lysate
  • PA5-21139 can be used with blocking peptide PEP-1253
  • SIK1 may mediate the physiological effects of LKB1, including its tumor suppressor function
  • SIK1 is also involved in signaling by various proteins like STRAD, NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4, and MELK that are related to AMPK
  • Activation of SIK1 by phosphorylation on thr322 can lead to an increase in the catalytic activity of sodium/potassium ATPase alpha subunit at the plasma membrane
  • This results in an increase in intracellular sodium in intact mammalian cells
  • The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains
  • The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K)
  • MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway
  • Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA521139

--


Antigen:
SIK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIK1

Gene Alias:
EIEE30; HRT-20; Kid2; MSK; Myocardial SNF1-like kinase; Probable serine/threonine protein kinase SNF1LK (HRT-20) (Myocardial SNF1-like kinase); protein kinase KID2; salt inducible kinase 1; salt-inducible kinase 1; salt-inducible protein kinase 1; serine/threonine protein kinase; serine/threonine-protein kinase SIK1; Serine/threonine-protein kinase SNF1-like kinase 1; serine/threonine-protein kinase SNF1LK; SIK; Sik1; SIK-1; SNF1-like kinase; SNF1LK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150094

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P57059

Gene Symbols:
SIK1

Immunogen:
An 18 amino acid peptide near the center of human SIK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521141

--


Antigen:
SPTLC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sptlc1

Gene Alias:
AW552086; C77762; E030036H05; fc75h04; fp41c08; hLCB1; HSAN; HSAN1; HSN1; hypothetical protein LOC553981; hypothetical protein LOC614165; LBC1; LCB 1; LCB1; long chain base biosynthesis protein 1; MGC14645; rCG_44191; RGD1306617; RP11-118F2.1; serine C-palmitoyltransferase; serine palmitoyltransferase 1; serine palmitoyltransferase long chain base subunit 1; serine palmitoyltransferase subunit 1; serine palmitoyltransferase, long chain base subunit 1; serine-palmitoyl-CoA transferase 1; SPT 1; Spt1; SPTI; sptlc1; wu:fc75h04; wu:fp41c08; zgc:112247

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10558

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O15269

Gene Symbols:
Sptlc1

Immunogen:
A 17 amino acid peptide near the carboxy terminus of human SPT1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521142

--


Antigen:
SPTLC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPTLC2

Gene Alias:
AI173915; hLCB2a; HSN1C; KIAA0526; LCB 2; LCB2; LCB2a; long chain base biosynthesis protein 2; Long chain base biosynthesis protein 2a; mKIAA0526; NSAN1C; Pomt2; protein-O-mannosyltransferase 2; serine palmitoyltransferase 2; serine palmitoyltransferase long chain base subunit 2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II; serine-palmitoyl-CoA transferase 2; SPT 2; SPT2; Sptlc2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20773, 9517

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O15270, P97363

Gene Symbols:
SPTLC2

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human SPT2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521143

--


Antigen:
NUMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Numb

Gene Alias:
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18222, 29419, 8650

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P49757, Q2LC84, Q9QZS3

Gene Symbols:
Numb

Immunogen:
A 17 amino acid peptide near the carboxy terminus of human NUMB.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG