PIPA521158

GEMC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA521158-Each-of-1 In Stock ₹ 44,705.10

PIPA521158 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GEMC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GMNC

Gene Alias

GEMC1; geminin coiled-coil domain containing; geminin coiled-coil domain-containing protein 1; Gm1778; Gm606; GMNC

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

239789, 647309

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

A6NCL1, Q3URY2

Gene Symbols

GMNC

Immunogen

A 19 amino acid peptide near the center of human GEMC1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is mouse heart tissue lysate
  • PA5-21158 can be used with blocking peptide PEP-1272
  • The Geminin coiled-coil domain-containing protein 1 (GEMC1) is a highly conserved protein that is required for chromosomal replication
  • GEMC1 contains a region similar to the coiled-coil domain of geminin, an essential vertebrate replication protein in which the coiled-coil domain is required for the function
  • GEMC1 binds to the checkpoint and replication factor TopBP1, allowing the binding of GEMC1 to chromatin during pre-replication complex formation
  • GEMC1 also directly interacts with replication factors Cdc45 and Cdk2-CyclinE and stimulates the initiation of DNA replication
  • Depletion of GEMC1 by siRNA in embryonic and somatic vertebrate cells prevents DNA replication due to impairment of Cdc45 loading onto chromatin, suggesting GEMC1 promotes initiation of DNA replication by mediating TopBP1 and Cdk2 dependent recruitment of Cdc45 onto replication origins.

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Thermo Scientific

PIPA521158

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Antigen:
GEMC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GMNC

Gene Alias:
GEMC1; geminin coiled-coil domain containing; geminin coiled-coil domain-containing protein 1; Gm1778; Gm606; GMNC

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
239789, 647309

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A6NCL1, Q3URY2

Gene Symbols:
GMNC

Immunogen:
A 19 amino acid peptide near the center of human GEMC1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521159

--


Antigen:
ATAD3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATAD3A

Gene Alias:
2400004H09Rik; AAA-ATPase TOB3; Atad3; ATAD3A; ATPase family AAA domain-containing protein 3; ATPase family AAA domain-containing protein 3A; ATPase family, AAA domain containing 3A; Kiaa1273; mKIAA1273; RP5-832C2.1; Tob3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108888, 298682, 55210

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q3KRE0, Q925I1, Q9NVI7

Gene Symbols:
ATAD3A

Immunogen:
A 19 amino acid peptide near the amino terminus of human ATAD3A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521160

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Antigen:
ATAD3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATAD3B

Gene Alias:
AAA-ATPase TOB3; AAA-TOB3; ATAD3B; ATPase family AAA domain-containing protein 3B; ATPase family, AAA domain containing 3B; KIAA1273; RP4-628J24.3; TOB3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83858

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5T9A4

Gene Symbols:
ATAD3B

Immunogen:
A 14 amino acid peptide near the carboxy terminus of human ATAD3B.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521161

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Antigen:
AP3S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP3S1

Gene Alias:
adapter-related protein complex 3 subunit sigma-1; adaptor related protein complex 3 sigma 1 subunit; adaptor related protein complex 3, sigma 1 subunit; adaptor-related protein complex 3 subunit sigma-1; adaptor-related protein complex 3, sigma 1 subunit; AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; AP3S1; CLAPS3; clathrin adaptor complex AP3, sigma-3A subunit; clathrin-associated/assembly/adapter protein, small 3; Clathrin-associated/assembly/adaptor protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD); Sigma3A; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1176, 11777, 302290

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q92572, Q9DCR2

Gene Symbols:
AP3S1

Immunogen:
A 19 amino acid peptide near the center of human AP3S1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG