PIPA521453

RAPGEF5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521453-Each-of-1 In Stock ₹ 44,705.10

PIPA521453 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RAPGEF5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RAPGEF5

Gene Alias

4932413M22; C86120; D030051B22Rik; GFR; guanine nucleotide exchange factor; guanine nucleotide exchange factor for Rap1; KIAA0277; mKIAA0277; mmr-gef; Mras regulated guanine nucleotide exchange factor; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MRGEF; MR-GEF; Rap guanine nucleotide exchange factor (GEF) 5; Rap guanine nucleotide exchange factor 5; RAPGEF5; Related to Epac; REPAC; RGD1562891; rMR-GEF; tcag7.1034

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9771

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.74 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q92565

Gene Symbols

RAPGEF5

Immunogen

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 179 of Human RAPGEF5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: H1299, HeLaS3
  • Predicted reactivity: Mouse (86%), Rhesus Monkey (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states
  • Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation
  • Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine
  • Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat
  • The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA521453

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Antigen:
RAPGEF5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAPGEF5

Gene Alias:
4932413M22; C86120; D030051B22Rik; GFR; guanine nucleotide exchange factor; guanine nucleotide exchange factor for Rap1; KIAA0277; mKIAA0277; mmr-gef; Mras regulated guanine nucleotide exchange factor; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MRGEF; MR-GEF; Rap guanine nucleotide exchange factor (GEF) 5; Rap guanine nucleotide exchange factor 5; RAPGEF5; Related to Epac; REPAC; RGD1562891; rMR-GEF; tcag7.1034

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9771

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.74 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q92565

Gene Symbols:
RAPGEF5

Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 179 of Human RAPGEF5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521455

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Antigen:
MPP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mpp3

Gene Alias:
6430514B01; CSG18; discs large homolog 3; discs, large homolog 3; DLG3; Dlgh3; Dusp3; MAGUK p55 subfamily member 3; MAGUK p55 subfamily member 3 {ECO:0000250; membrane palmitoylated protein 3; membrane protein palmitoylated 3; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3); Mpp3; mpp3 {ECO:0000312; Mpp3 membrane protein, palmitoylated 3; protein Dlgh3; protein MPP3; RGD:620015}; UniProtKB:O88910}

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4356

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13368

Gene Symbols:
Mpp3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 270 and 585 of MPP3 (Uniprot ID#Q13368)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521457

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Antigen:
RAP1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAP1A

Gene Alias:
AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5906

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, 0.025% ProClin 300; pH 7

Gene Accession No.:
P62834

Gene Symbols:
RAP1A

Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 134 (P62834) of RAP1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521458

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Antigen:
NEK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEK4

Gene Alias:
Nek4; Never in mitosis A-related kinase 4; NIMA (never in mitosis gene a)-related expressed kinase 4; NIMA (never in mitosis gene a)-related kinase 4; NIMA related kinase 4; NIMA-related kinase 4; nimA-related protein kinase 4; NRK2; pp12301; serine/threonine kinase 2; serine/threonine protein kinase-2; serine/threonine-protein kinase 2; Serine/threonine-protein kinase Nek4; serine/threonine-protein kinase Nek4 variant 2; serine/threonine-protein kinase NRK2; STK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6787

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.37 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P51957

Gene Symbols:
NEK4

Immunogen:
Recombinant fragment corresponding to a region within amino acids 241 and 504 of NEK4 (Uniprot ID#P51957)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG