PIPA521685

PFKL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521685-Each-of-1 In Stock ₹ 47,785.26

PIPA521685 - Each of 1

₹ 47,785.26

In Stock

Quantity

1

Base Price: ₹ 47,785.26

GST (18%): ₹ 8,601.347

Total Price: ₹ 56,386.607

Antigen

PFKL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PFKL

Gene Alias

6-phosphofructokinase type B; 6-phosphofructokinase, liver type; AA407869; ATP-dependent 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; EC 2.7.1.11; HAMAP-Rule:MF_03184}; K6PL; liver-type 1-phosphofructokinase; Pfkb; PFK-B; Pfkl; Pfk-l; Phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphofructokinase, liver; phosphofructokinase, liver type; phosphofructokinase, liver, B-type; phosphohexokinase; phosphohexokinase {ECO:0000255

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18641, 5211

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.8 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P12382, P17858

Gene Symbols

PFKL

Immunogen

Recombinant fragment corresponding to a region within amino acids 428 and 674 of PFKL (Uniprot ID#P17858)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA521931

--

Img

Thermo Scientific

PIPA522144

--

Img

Thermo Scientific

PIPA521691

--

Img

Thermo Scientific

PIPA521964

--

Img

Thermo Scientific

PIPA521510

--

Img

Thermo Scientific

PIPA522024

--

Img

Thermo Scientific

PIPA521817

--

Img

Thermo Scientific

PIPA522336

--

Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2
  • Predicted reactivity: Mouse (95%), Rat (95%), Chicken (88%), Bovine (94%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Phosphofructokinase (PFK), a major regulatory enzyme in all cells of the body, catalyzes the metabolism of sugar, and thereby is pivotal in the production of energy to maintain normal cell function
  • In human there are three structural loci controlling PFK: M (muscle), L (liver), and P (platelet) type subunits, which are variably expressed in different tissues; human diploid fibroblasts and leukocytes express all three genes
  • PFK, a tetramer formed by the random association of the products of two separate gene loci to form the five possible tetramers
  • PFKs of muscle and liver are homotetramers of the M and L subunits, respectively
  • Red cells have all five isozymes: M4, M3L, M2L2, ML3, and L4
  • PFK is an allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate
  • PFK catalyzes the key controlling step of glycolytic pathway
  • PFK deficiency can present as mild to life-threatening episodic illness
  • A hallmark sign of this disease is intermittent dark urine, with the color of the urine ranging from orange to dark coffee-brown, which commonly develops following strenuous exercise
  • The mean red cell PFK is elevated in persons with Down syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA521685

--


Antigen:
PFKL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PFKL

Gene Alias:
6-phosphofructokinase type B; 6-phosphofructokinase, liver type; AA407869; ATP-dependent 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; EC 2.7.1.11; HAMAP-Rule:MF_03184}; K6PL; liver-type 1-phosphofructokinase; Pfkb; PFK-B; Pfkl; Pfk-l; Phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphofructokinase, liver; phosphofructokinase, liver type; phosphofructokinase, liver, B-type; phosphohexokinase; phosphohexokinase {ECO:0000255

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18641, 5211

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.8 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P12382, P17858

Gene Symbols:
PFKL

Immunogen:
Recombinant fragment corresponding to a region within amino acids 428 and 674 of PFKL (Uniprot ID#P17858)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521687

--


Antigen:
STAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAR

Gene Alias:
AV363654; cholesterol trafficker; D8Ertd419e; lipid transporter; luteinizing hormone-induced protein; mitochondrial steroid acute regulatory protein; STAR; StAR related lipid transfer (START) domain containing 1; stARD1; StAR-related lipid transfer (START) domain containing 1; START domain containing 1; START domain-containing protein 1; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein; steroidogenic acute regulatory protein, mitochondrial; testis secretory sperm-binding protein Li 241mP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20845, 6770

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P49675, P51557

Gene Symbols:
STAR

Immunogen:
Recombinant fragment corresponding to a region within amino acids 15 and 268 of STAR (Uniprot ID#P49675)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521688

--


Antigen:
NT5C2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NT5C2

Gene Alias:
2010002I23Rik; 5'-nucleotidase (purine), cytosolic type B; 5'-nucleotidase, cytosolic II; CnII; cN-II; Cytosolic 5'-nucleotidase II; cytosolic purine 5'-nucleotidase; ENSMUSG00000025039; Gm9751; Gmp; IMP-specific 5'-NT; Nt5b; Nt5c2; NT5CP; PNT5; RP11-30H12.3; SPG45; SPG65

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22978, 76952

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P49902, Q3V1L4

Gene Symbols:
NT5C2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 108 and 362 of NT5C2 (Uniprot ID#P49902)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521691

--


Antigen:
INPP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INPP1

Gene Alias:
2300002C06Rik; AV137389; Inositol polyphosphate 1-phosphatase; inositol polyphosphate-1-phosphatase; Inpp1; IPP; IPPase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3628

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.84 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P49441

Gene Symbols:
INPP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 3 and 269 of INPP1 (Uniprot ID#P49441)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG