PIPA521877
NLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521877-Each-of-1 | In Stock | ₹ 50,223.72 |
PIPA521877 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,223.72
GST (18%): ₹ 9,040.27
Total Price: ₹ 59,263.99
Antigen
NLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18099, 51701
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O54949, Q9UBE8
Gene Symbols
NLK
Immunogen
Recombinant fragment corresponding to a region within amino acids 234 and 527 of NLK (Uniprot ID#Q9UBE8)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: NLK-transfected 293T, A431, H1299, HeLa, mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (98%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
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Antigen: NLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18099, 51701
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O54949, Q9UBE8
Gene Symbols: NLK
Immunogen: Recombinant fragment corresponding to a region within amino acids 234 and 527 of NLK (Uniprot ID#Q9UBE8)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18099, 51701
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O54949, Q9UBE8
Gene Symbols:
NLK
Immunogen:
Recombinant fragment corresponding to a region within amino acids 234 and 527 of NLK (Uniprot ID#Q9UBE8)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PRAK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPKAPK5
Gene Alias: MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8550
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.62 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q8IW41
Gene Symbols: MAPKAPK5
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 197 and 457 (Q8IW41) of PRAK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PRAK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPKAPK5
Gene Alias:
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8550
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.62 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q8IW41
Gene Symbols:
MAPKAPK5
Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 197 and 457 (Q8IW41) of PRAK
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NUP62
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nup62
Gene Alias: 62 kDa nucleoporin; AA589433; AI426861; AI790512; AU045898; D7Ertd649e; DKFZp547L134; FLJ20822; FLJ43869; IBSN; MGC841; Np62; nuclear pore complex 1; nuclear pore glycoprotein 62; nuclear pore glycoprotein p62; nucleoporin 62; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin Nup62; nucleoporin p62; Nup62; Nupc1; p62; SNDI
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18226, 23636, 65274
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P17955, P37198, Q63850
Gene Symbols: Nup62
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 230 and 490 (P37198) of Nucleoporin p62
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NUP62
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nup62
Gene Alias:
62 kDa nucleoporin; AA589433; AI426861; AI790512; AU045898; D7Ertd649e; DKFZp547L134; FLJ20822; FLJ43869; IBSN; MGC841; Np62; nuclear pore complex 1; nuclear pore glycoprotein 62; nuclear pore glycoprotein p62; nucleoporin 62; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin Nup62; nucleoporin p62; Nup62; Nupc1; p62; SNDI
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18226, 23636, 65274
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P17955, P37198, Q63850
Gene Symbols:
Nup62
Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 230 and 490 (P37198) of Nucleoporin p62
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ITPK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITPK1
Gene Alias: BC031182; inositol 1,3,4-triphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-tetrakisphosphate 1-kinase; inositol-triphosphate 5/6-kinase; ins(1,3,4)P(3) 5/6-kinase; ITPK1; ITRPK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 217837, 3705
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.53 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13572, Q8BYN3
Gene Symbols: ITPK1
Immunogen: Recombinant fragment corresponding to a region within amino acids 171 and 414 of ITPK1 (Uniprot ID#Q13572)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ITPK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITPK1
Gene Alias:
BC031182; inositol 1,3,4-triphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-tetrakisphosphate 1-kinase; inositol-triphosphate 5/6-kinase; ins(1,3,4)P(3) 5/6-kinase; ITPK1; ITRPK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
217837, 3705
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.53 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13572, Q8BYN3
Gene Symbols:
ITPK1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 171 and 414 of ITPK1 (Uniprot ID#Q13572)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG