PIPA521958

ZO-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521958-Each-of-1 In Stock ₹ 47,271.90

PIPA521958 - Each of 1

₹ 47,271.90

In Stock

Quantity

1

Base Price: ₹ 47,271.90

GST (18%): ₹ 8,508.942

Total Price: ₹ 55,780.842

Antigen

ZO-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TJP1

Gene Alias

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7082

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q07157

Gene Symbols

TJP1

Immunogen

Recombinant fragment corresponding to a region within amino acids 1574 and 1748 of ZO-1 (Uniprot ID#Q07157)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HCT116, 293T, A431, HeLa
  • Predicted reactivity: Mouse (99%), Rat (99%), Dog (84%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ZO-1 forms complexes with either ZO-2 or ZO-3
  • In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
  • ZO-1 expression is significantly reduced in many breast cancer lines
  • ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
  • ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions
  • ZO-1 may be involved in signal transduction at cell-cell junctions
  • Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene
  • Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA521958

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Antigen:
ZO-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TJP1

Gene Alias:
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1574 and 1748 of ZO-1 (Uniprot ID#Q07157)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521959

--


Antigen:
Profilin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PFN2

Gene Alias:
D3S1319E; PFL; Pfn; PFN2; profilin 2; profilin II; Profilin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18645, 5217, 81531

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P35080, Q9EPC6, Q9JJV2

Gene Symbols:
PFN2

Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 90 (P35080) of Profilin 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521960

--


Antigen:
RAP2C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAP2C

Gene Alias:
2010200P20Rik; AI194294; AL022976; RAP2C; RAP2C, member of RAS oncogene family; ras-related protein Rap-2c; small GTPase RAP2C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57826

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9Y3L5

Gene Symbols:
RAP2C

Immunogen:
Full length human RAP2C Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA521962

--


Antigen:
RAB2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB2B

Gene Alias:
1500012D09Rik; 4930528G15Rik; A230002G14; D530043M21Rik; GTP-binding protein RAB2B; Rab2b; RAB2B, member RAS oncogene family; RAS family, member RAB2B; ras-related protein Rab-2B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
76338, 84932

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.83 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P59279, Q8WUD1

Gene Symbols:
RAB2B

Immunogen:
Full length human RAB2B Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG