PIPA521983

CtIP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521983-Each-of-1 In Stock ₹ 50,394.84

PIPA521983 - Each of 1

₹ 50,394.84

In Stock

Quantity

1

Base Price: ₹ 50,394.84

GST (18%): ₹ 9,071.071

Total Price: ₹ 59,465.911

Antigen

CtIP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5932

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ChIP Assay, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q99708

Gene Symbols

Rbbp8

Immunogen

Recombinant fragment corresponding to a region within amino acids 452 and 777 of CtIP (Uniprot ID#Q99708)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2, Raji
  • Predicted reactivity: Rhesus Monkey (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

Compare Similar Items

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Thermo Scientific

PIPA521983

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Antigen:
CtIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5932

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99708

Gene Symbols:
Rbbp8

Immunogen:
Recombinant fragment corresponding to a region within amino acids 452 and 777 of CtIP (Uniprot ID#Q99708)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA521987

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Antigen:
LIMK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LIMK2

Gene Alias:
EC 2.7.11.1; kinase LIMK2; LIM domain kinase 2; LIM kinase 2; LIM motif-containing protein kinase 2; LIMK; LIMK 2; LIMK1; LIMK-1; Limk2; LIMK-2; Limk2b; LINhp-2; Link2; OTTHUMP00000199483

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3985

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P53671

Gene Symbols:
LIMK2

Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 252 (P53671) of LIM kinase 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA521988

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Antigen:
B3GNT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
B3gnt3

Gene Alias:
2210008L19Rik; B3GALT8; B3GAL-T8; B3gnt3; B3GN-T3; B3GNT-3; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-galactosyltransferase 8; Beta-1,3-GalTase 8; beta-1,3-Gn-T3; beta-1,3-N-acetylglucosaminyltransferase 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; beta3GalT8; beta3Gn-T3; beta-3-Gx-T8; BGnT-3; core 1 beta-1,3-N-acetylglucosaminyltransferase; core 1 extending beta-1,3-N-acetylglucosaminyltransferase; Core1-beta3GlcNAcT; HP10328; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; putative type II membrane protein; TMEM3; Transmembrane protein 3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; UNQ637/PRO1266

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10331, 72297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q5JCS9, Q9Y2A9

Gene Symbols:
B3gnt3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 122 and 338 of B3GNT3 (Uniprot ID#Q9Y2A9)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA521990

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Antigen:
SNTB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNTB2

Gene Alias:
59 kDa dystrophin-associated protein A1 basic component 2; beta-2-syntrophin; D16S2531E; dystrophin-associated protein A1, 59kD, basic component 2; EST25263; Snt2; SNT2B2; SNT3; SNTB2; SNTL; SYN; syntrophin beta 2; syntrophin, basic 2; syntrophin, beta 2; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); syntrophin-3; Syntrophin-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6645

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.84 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13425

Gene Symbols:
SNTB2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 174 and 540 of SNTB2 (Uniprot ID#Q13425)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG