PIPA522230

IFIT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA522230-Each-of-1 In Stock ₹ 47,699.70

PIPA522230 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

IFIT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFIT3

Gene Alias

cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; P49; P60; retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15959, 3437

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

O14879, Q64345

Gene Symbols

IFIT3

Immunogen

Recombinant fragment corresponding to a region within amino acids 230 and 490 of IFIT3 (Uniprot ID#O14879)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T
  • Predicted reactivity: Chimpanzee (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication
  • Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription
  • Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27
  • Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation
  • IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels
  • Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21
  • Can negatively regulate the apoptotic effects of IFIT2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA522230

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; P49; P60; retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15959, 3437

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
O14879, Q64345

Gene Symbols:
IFIT3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 230 and 490 of IFIT3 (Uniprot ID#O14879)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522231

--


Antigen:
INPP5B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INPP5B

Gene Alias:
5PTase; 75 kDa inositol polyphosphate-5-phosphatase; AW260155; inositol polyphosphate-5-phosphatase B; inositol polyphosphate-5-phosphatase, 75kDa; INPP5B; INPP5P; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; MGC65156; MGC71303; OCRL2; Phosphoinositide 5-phosphatase; RP11-109P14.7; type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol 1,4,5-trisphosphate 5-phosphatase; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3633

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.34 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P32019

Gene Symbols:
INPP5B

Immunogen:
Recombinant fragment corresponding to a region within amino acids 699 and 949 of INPP5B (Uniprot ID#P32019)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA522233

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Antigen:
LETM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LETM1

Gene Alias:
LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial; leucine zipper and EF-hand containing transmembrane protein 1; leucine zipper-EF-hand containing transmembrane protein 1; leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; Mitochondrial proton/calcium exchanger protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3954, 56384

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95202, Q9Z2I0

Gene Symbols:
LETM1

Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 506 and 723 (O95202) of LETM1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522234

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Antigen:
RCBTB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rcbtb2

Gene Alias:
2610028E02Rik; 2810420M18Rik; AI448345; AW240694; CHC1L; CHC1-L; Chromosome condensation 1-like; RC/BTB2; Rcbtb2; RCC1 and BTB domain containing protein 2; RCC1 and BTB domain-containing protein 2; RCC1-like G exchanging factor; RCC1-like G exchanging factor RLG; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2; regulator of chromosome condensation and BTB domain-containing protein 2; RLG

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1102

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.32 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95199

Gene Symbols:
Rcbtb2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 214 and 472 of RCBTB2 (Uniprot ID#O95199)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG