PIPA522778
HIF1A Polyclonal Antibody, DyLight™ 488, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA522778-Each-of-1 | In Stock | ₹ 46,074.06 |
PIPA522778 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,074.06
GST (18%): ₹ 8,293.331
Total Price: ₹ 54,367.391
Antigen
HIF1A
Classification
Polyclonal
Conjugate
DyLight 488
Gene
HIF1A
Gene Alias
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage
4° C, store in dark
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
0.65 mg/mL
Formulation
50mM sodium borate with 0.05% sodium azide
Gene Accession No.
O35800, Q16665, Q61221
Gene Symbols
HIF1A
Immunogen
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody detects upregulation of HIF-1 alpha in hypoxic samples
- HIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension
- HIF-1 is a heterodimer consisting of an alpha and beta subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors
- HIF1 functions as a transcriptional regulator of the adaptive response to hypoxia
- Under hypoxic conditions, HIF-1 activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia
- HIF1-alpha regulates hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
- Hypoxia which induces p53 protein accumulation, directly interacts with HIF1-alpha and reduces hypoxia-induced expression of HIF1-alpha by promoting MDM2-mediated ubiquitination and proteasomal degradation under hypoxic conditions
- Recent studies suggest that induction of NOX4 by HIF1-alpha contributes to maintain ROS levels after hypoxia and hypoxia-induced proliferation
- In humans, it is located on the q arm of chromosome 14
- The C-terminal of HIF1A binds to p300
- p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF
- Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease.
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Antigen: HIF1A
Classification: Polyclonal
Conjugate: DyLight 488
Gene: HIF1A
Gene Alias: AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.65 mg/mL
Formulation: 50mM sodium borate with 0.05% sodium azide
Gene Accession No.: O35800, Q16665, Q61221
Gene Symbols: HIF1A
Immunogen: A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HIF1A
Classification:
Polyclonal
Conjugate:
DyLight 488
Gene:
HIF1A
Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.65 mg/mL
Formulation:
50mM sodium borate with 0.05% sodium azide
Gene Accession No.:
O35800, Q16665, Q61221
Gene Symbols:
HIF1A
Immunogen:
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HIF1A
Classification: Polyclonal
Conjugate: HRP
Gene: HIF1A
Gene Alias: AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L home
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.73 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O35800, Q16665, Q61221
Gene Symbols: HIF1A
Immunogen: A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HIF1A
Classification:
Polyclonal
Conjugate:
HRP
Gene:
HIF1A
Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L home
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.73 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O35800, Q16665, Q61221
Gene Symbols:
HIF1A
Immunogen:
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HIF1A
Classification: Polyclonal
Conjugate: DyLight 550
Gene: HIF1A
Gene Alias: AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.84 mg/mL
Formulation: 50mM sodium borate with 0.05% sodium azide
Gene Accession No.: O35800, Q16665, Q61221
Gene Symbols: HIF1A
Immunogen: A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HIF1A
Classification:
Polyclonal
Conjugate:
DyLight 550
Gene:
HIF1A
Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.84 mg/mL
Formulation:
50mM sodium borate with 0.05% sodium azide
Gene Accession No.:
O35800, Q16665, Q61221
Gene Symbols:
HIF1A
Immunogen:
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: OS9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OS9
Gene Alias: 4632413K17Rik; amplified in osteosarcoma; amplified in osteosarcoma 9; AU022351; endoplasmic reticulum lectin 2; ERLEC2; erlectin 2; OS9; Os-9; OS9 endoplasmic reticulum lectin; OS9, endoplasmic reticulum lectin; osteosarcoma amplified 9; osteosarcoma amplified 9, endoplasmic reticulum associated protein; osteosarcoma amplified 9, endoplasmic reticulum lectin; protein OS-9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10956, 216440
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: tris citrate, tris phosphate with 0.01% sodium azide; pH 7-8
Gene Accession No.: Q13438, Q8K2C7
Gene Symbols: OS9
Immunogen: Synthetic peptide made to an internal portion of isoform 1 of the human OS9 protein (within residues 300-400).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
OS9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OS9
Gene Alias:
4632413K17Rik; amplified in osteosarcoma; amplified in osteosarcoma 9; AU022351; endoplasmic reticulum lectin 2; ERLEC2; erlectin 2; OS9; Os-9; OS9 endoplasmic reticulum lectin; OS9, endoplasmic reticulum lectin; osteosarcoma amplified 9; osteosarcoma amplified 9, endoplasmic reticulum associated protein; osteosarcoma amplified 9, endoplasmic reticulum lectin; protein OS-9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10956, 216440
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
tris citrate, tris phosphate with 0.01% sodium azide; pH 7-8
Gene Accession No.:
Q13438, Q8K2C7
Gene Symbols:
OS9
Immunogen:
Synthetic peptide made to an internal portion of isoform 1 of the human OS9 protein (within residues 300-400).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG