PIPA522785

LYVE1 Polyclonal Antibody, Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA522785-Each-of-1 In Stock ₹ 47,015.22

PIPA522785 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

LYVE1

Classification

Polyclonal

Conjugate

Biotin

Gene

Lyve1

Gene Alias

1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10894, 114332

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Western Blot

Concentration

0.9 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q8BHC0, Q9Y5Y7

Gene Symbols

Lyve1

Immunogen

A synthetic peptide made to a C-terminal portion of the human LYVE-1 protein sequence (between residues 250-322).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: mouse spleen lysate
  • LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall
  • The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily
  • Like CD44, the LYVE1 molecule binds both soluble and immobilized HA
  • However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels
  • Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves
  • LYVE1 is a type I integral membrane glycoprotein
  • LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumor cells to lymph nodes
  • The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen
  • A number of molecules have been identified as markers for lymphatic endothelium which include LYVE1, PALE, VEGFR3, and podoplanin
  • Diseases associated with LYVE1 dysfunction includes Complete Androgen Insensitivity Syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA522785

--


Antigen:
LYVE1

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Lyve1

Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10894, 114332

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Western Blot

Concentration:
0.9 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8BHC0, Q9Y5Y7

Gene Symbols:
Lyve1

Immunogen:
A synthetic peptide made to a C-terminal portion of the human LYVE-1 protein sequence (between residues 250-322).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522786

--


Antigen:
LYVE1

Classification:
Polyclonal

Conjugate:
DyLight 650

Gene:
Lyve1

Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10894, 114332

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Western Blot

Concentration:
0.55 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q8BHC0, Q9Y5Y7

Gene Symbols:
Lyve1

Immunogen:
A synthetic peptide made to a C-terminal portion of the human LYVE-1 protein sequence (between residues 250-322).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522787

--


Antigen:
LYVE1

Classification:
Polyclonal

Conjugate:
DyLight 488

Gene:
Lyve1

Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10894, 114332

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Western Blot

Concentration:
0.69 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q8BHC0, Q9Y5Y7

Gene Symbols:
Lyve1

Immunogen:
A synthetic peptide made to a C-terminal portion of the human LYVE-1 protein sequence (between residues 250-322).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522791

--


Antigen:
53BP1

Classification:
Polyclonal

Conjugate:
DyLight 650

Gene:
TP53BP1

Gene Alias:
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27223, 7158

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.62 mg/mL

Formulation:
50mM sodium borate with no preservative

Gene Accession No.:
P70399, Q12888

Gene Symbols:
TP53BP1, Trp53bp1

Immunogen:
A synthetic peptide corresponding to a portion of human 53BP1 encoded in exon 11, 12 and 19 [Uniprot: Q12888]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG