PIPA522974

JMJD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA522974-Each-of-1 In Stock ₹ 47,699.70

PIPA522974 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

JMJD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KDM6B

Gene Alias

1700064E03Rik; BC038313; jmjC domain-containing protein 3; JMJD3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; KIAA0346; lysine (K)-specific demethylase 6B; lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

216850, 23135

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

O15054, Q5NCY0

Gene Symbols

KDM6B

Immunogen

Synthetic peptide made to an internal portion of the mouse protein (within residues 600-650).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The target sequence has 100% sequence homology with rat
  • Covalent modification of histones plays critical role in regulating chromatin structure and transcription
  • While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones
  • A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function
  • Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate
  • Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9)
  • Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

Compare Similar Items

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Img

Thermo Scientific

PIPA522974

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Antigen:
JMJD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM6B

Gene Alias:
1700064E03Rik; BC038313; jmjC domain-containing protein 3; JMJD3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; KIAA0346; lysine (K)-specific demethylase 6B; lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
216850, 23135

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O15054, Q5NCY0

Gene Symbols:
KDM6B

Immunogen:
Synthetic peptide made to an internal portion of the mouse protein (within residues 600-650).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522975

--


Antigen:
NBS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NBN

Gene Alias:
AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27354, 4683

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.48 mg/mL

Formulation:
PBS with 30% glycerol and 0.1% sodium azide

Gene Accession No.:
O60934, Q9R207

Gene Symbols:
NBN

Immunogen:
Synthetic peptide made to an internal portion of the mouse protein (within residues 150-200).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522976

--


Antigen:
LDLR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LDLR

Gene Alias:
FH; FHC; Hlb301; I79_005860; LDL receptor; LDLA; LDLCQ2; LDLR; ldl-r; LDLRA; low density lipoprotein receptor; low density lipoprotein receptor protein; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16835, 3949

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P01130, P35951

Gene Symbols:
LDLR

Immunogen:
Synthetic peptide made to an internal portion of the human protein (within residues 500-550).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522984

--


Antigen:
PDK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdk4

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AV005916; kinase isozyme 4; lipoamide; PDHK4; Pdk4; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 4; Pyruvate dehydrogenase kinase isoform 4; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase kinase, isozyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; pyruvate dehydrogenate kinase 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5166

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.24 mg/mL

Formulation:
PBS with 30% glycerol and 0.1% sodium azide

Gene Accession No.:
Q16654

Gene Symbols:
Pdk4

Immunogen:
Synthetic peptide made to an internal portion of the human protein (within residues 200-250).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG