PIPA523297

EBI3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523297-Each-of-1 In Stock ₹ 47,528.58

PIPA523297 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

EBI3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EBI3

Gene Alias

cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10148, 50498, 680609

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O35228, Q14213

Gene Symbols

EBI3

Immunogen

A portion of amino acids 180-228 of mouse EBI3

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family
  • It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function
  • EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively
  • IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation
  • It negatively regulates Th17 cell differentiation
  • EBI3 is widely expressed and its expression in dendritic cell is transcriptionally regulated by TLR signaling via MyD88 and NF-kappaB during innate immune responses preceding cytokine driven Th cell development
  • EBI3 signal inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction
  • EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma
  • Targeted deletion of EBI3 protects mice from lung metastasis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA523297

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Antigen:
EBI3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EBI3

Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10148, 50498, 680609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35228, Q14213

Gene Symbols:
EBI3

Immunogen:
A portion of amino acids 180-228 of mouse EBI3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA523298

--


Antigen:
RAP2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAP2A

Gene Alias:
5830461H18Rik; KREV; K-REV; RAP2; RAP2, member of RAS oncogene family (K-rev); Rap2a; Rap2A GTPase; RAP2A, member of RAS oncogene family; RAS related protein 2a; ras-related protein Rap-2a; RbBP-30; RP11-128N14.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100060181, 414291, 476968, 5911, 76108, 769797

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P10114, Q80ZJ1

Gene Symbols:
RAP2A

Immunogen:
A portion of amino acids 140-183 of human RAP2A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Chicken, Equine, Human, Marsupial, Mouse, Non-human Primate, X. laevis

Product Type:
Antibody

Isotype:
IgG

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PIPA523300

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Antigen:
G6B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mpig6b

Gene Alias:
AU023871; C6orf25; chromosome 6 open reading frame 25; DADB-110M10.2; G6b; G6B-B; immunoglobulin receptor; immunoreceptor tyrosine-based inhibitory motif (ITIM) containing platelet receptor; Immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing platelet receptor; ITIM-receptor G6b-B; Megakaryocyte and platelet inhibitory receptor G6b; MPIG6B; NG31; Protein G6b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
80739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O95866

Gene Symbols:
Mpig6b

Immunogen:
A portion of amino acids 170-220 of human G6B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA523301

--


Antigen:
GARP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRRC32

Gene Alias:
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2615, 293135, 434215

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
G3XA59, Q14392

Gene Symbols:
LRRC32

Immunogen:
A portion of amino acids 250-300 of human GARP/LRRC32

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG