PIPA523497

RIG-I Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523497-Each-of-1 In Stock ₹ 50,309.28

PIPA523497 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

RIG-I

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

A portion of amino acid 200-250 of human RIG-I

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

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Img

Thermo Scientific

PIPA523497

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Antigen:
RIG-I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
A portion of amino acid 200-250 of human RIG-I

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523498

--


Antigen:
HES5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HES5

Gene Alias:
BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15208, 388585, 79225

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P70120, Q03062, Q5TA89

Gene Symbols:
HES5

Immunogen:
A portion of amino acid 1-50 of human HES5

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523500

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Antigen:
CACTIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CACTIN

Gene Alias:
2510012J08Rik; C19orf29; C20H19orf29; CACTIN; cactin, spliceosome C complex subunit; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24; NY-REN-24 antigen; renal carcinoma antigen NY-REN-24; RGD1563634

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100521180, 485055, 58509

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q8WUQ7

Gene Symbols:
CACTIN

Immunogen:
A portion of amino acid 460-510 of human Cactin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523501

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Antigen:
SPIB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPIB

Gene Alias:
B42b-like; Ets transcription factor Spi-B; Spi-1/PU.1 related; Spib; SPI-B; Spi-B transcription factor; Spi-B transcription factor (Spi-1/PU.1 related); Transcription factor Spi-B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100688036, 102150831, 272382, 6689, 784460

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O35906, Q01892

Gene Symbols:
SPIB

Immunogen:
A portion of amino acid 15-65 of human Spi-B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Equine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG