PIPA523939

Claudin 16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA523939-Each-of-1 In Stock ₹ 44,705.10

PIPA523939 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Claudin 16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CLDN16

Gene Alias

claudin 16; claudin-16; claudin-16; LOW QUALITY PROTEIN: claudin-16; CLDN16; H59D2a protein; HOMG3; hypomagnesemia 3, with hypercalciuria and nephrocalcinosis; paracellin-1; PCLN1; PCLN-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10686

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q9Y5I7

Gene Symbols

CLDN16

Immunogen

KLH conjugated synthetic peptide between 6-33 amino acids from the N-terminal region of human CLDN16

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Tight junction group of proteins are a cell-to-cell adhesion structure in epithelial cells that constitute the epithelial junctional complex with adherens junctions and desmosomes
  • Tight junction strands are mainly composed of claudins, occludin, and JAM
  • Claudin-16 belongs to the Claudin family of protein which is composed of 23 integral membrane proteins
  • Claudins are responsible for the formation of tight junction strands and are connected with the actin cytoskeleton mediated by ZO-1
  • Claudin 16, also known as Paracellin-1, is a renal tight junction protein required for paracellular magnesium resorption
  • It is localized in the intercellular junctions of the epithelial cells of the thick ascending limb of Henle's loop (a TAL marker) are used to localize this specific structure of nephrons in kidney sections
  • Mg2+ resorption occurs in TAL, and Claudin-16 is required for this paracellular function
  • Failure in renal 'handling' of magnesium can result in hypermagnesemia, whose major direct toxicity implications are cardiovascular as well as renal failure
  • Recent studies have shown that the lack of Claudin-16 proteins contributes to the dysfunction of paracellular renal transport systems.

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Show Difference

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Thermo Scientific

PIPA523939

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Antigen:
Claudin 16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLDN16

Gene Alias:
claudin 16; claudin-16; claudin-16; LOW QUALITY PROTEIN: claudin-16; CLDN16; H59D2a protein; HOMG3; hypomagnesemia 3, with hypercalciuria and nephrocalcinosis; paracellin-1; PCLN1; PCLN-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10686

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9Y5I7

Gene Symbols:
CLDN16

Immunogen:
KLH conjugated synthetic peptide between 6-33 amino acids from the N-terminal region of human CLDN16

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA523954

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Antigen:
Angiopoietin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Angpt1

Gene Alias:
1110046O21Rik; 2810039D03Rik; AGP1; Agpt; Agpt1; ANG1; ang-1; ANG3; ANG-3; angioarrestin; angiopoietin 1; angiopoietin 3; angiopoietin like 1; angiopoietin Y1; angiopoietin-1; Angiopoietin-3; angiopoietin-like 1; angiopoietin-like protein 1; Angiopoietin-related protein 1; Angpt1; ANGPT3; Angptl1; AngY; ARP1; dJ595C2.2; dJ595C2.2 (angiopoietin Y1); endothelial growth factor; KIAA0003; PSEC0154; tie2 receptor ligand; UNQ162; UNQ162/PRO188

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
284

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q15389

Gene Symbols:
Angpt1

Immunogen:
KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA523956

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Antigen:
DDX11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX11

Gene Alias:
4732462I11Rik; ATP-dependent DNA helicase DDX11; CHL1; CHL1-like helicase homolog; CHL1-related helicase gene-1; CHL1-related protein 1; CHLR1; DDX11; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); DEAD/H box protein 11; DEAD/H-box helicase 11; DEAD/H-box protein 11; essa15a; hCHLR1; Keratinocyte growth factor-regulated gene 2 protein; KRG2; KRG-2; probable ATP-dependent DNA helicase DDX11; probable ATP-dependent RNA helicase DDX11; WABS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1663, 320209

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6AXC6, Q96FC9

Gene Symbols:
DDX11

Immunogen:
KLH conjugated synthetic peptide between 656-683 amino acids from the central region of human DDX11

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA523960

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Antigen:
PAX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAX1

Gene Alias:
hbs; hunchback; HuP48; OFC2; paired box 1; paired box gene 1; Paired box homeotic gene 1; paired box protein Pax-1; paired domain gene HuP48; PAX1; Pax-1; un; undulated; wavy tail; wt

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5075

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P15863

Gene Symbols:
PAX1

Immunogen:
KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human PAX1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG