PIPA524453
DTL Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA524453-Each-of-1 | In Stock | ₹ 44,790.66 |
PIPA524453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,790.66
GST (18%): ₹ 8,062.319
Total Price: ₹ 52,852.979
Antigen
DTL
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DTL
Gene Alias
2810047L02Rik; 5730564G15Rik; CDT2; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; DDB1- and CUL4-associated factor 2; denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; DTL; L2dtl; lethal(2) denticleless protein homolog; Meth A RAMP; Meth A retinoic acid-regulated nuclear matrix-associated protein; RA regulated nuclear matrix associated protein; RAMP; RA-regulated nuclear matrix-associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RGD1310439
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
51514, 76843
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q3TLR7, Q9NZJ0
Gene Symbols
DTL
Immunogen
KLH conjugated synthetic peptide between 229-256 amino acids from the central region of human DTL
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis
- The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1)
- CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication
- CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing
- Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation
- In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Compare Similar Items
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Antigen: DTL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DTL
Gene Alias: 2810047L02Rik; 5730564G15Rik; CDT2; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; DDB1- and CUL4-associated factor 2; denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; DTL; L2dtl; lethal(2) denticleless protein homolog; Meth A RAMP; Meth A retinoic acid-regulated nuclear matrix-associated protein; RA regulated nuclear matrix associated protein; RAMP; RA-regulated nuclear matrix-associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RGD1310439
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 51514, 76843
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q3TLR7, Q9NZJ0
Gene Symbols: DTL
Immunogen: KLH conjugated synthetic peptide between 229-256 amino acids from the central region of human DTL
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DTL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DTL
Gene Alias:
2810047L02Rik; 5730564G15Rik; CDT2; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; DDB1- and CUL4-associated factor 2; denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; DTL; L2dtl; lethal(2) denticleless protein homolog; Meth A RAMP; Meth A retinoic acid-regulated nuclear matrix-associated protein; RA regulated nuclear matrix associated protein; RAMP; RA-regulated nuclear matrix-associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RGD1310439
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
51514, 76843
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q3TLR7, Q9NZJ0
Gene Symbols:
DTL
Immunogen:
KLH conjugated synthetic peptide between 229-256 amino acids from the central region of human DTL
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ZC3H12A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZC3H12A
Gene Alias: BC036563; bifunctional endoribonuclease and deubiquitinase ZC3H12A; dJ423B22.1; Endoribonuclease ZC3H12A; MCP-1 treatment-induced protein; MCP-induced protein 1; MCPIP; MCPIP1; Monocyte chemotactic protein-induced protein 1; Reg1; Regnase-1; RGD:1306776}; RGD1306776; ribonuclease ZC3H12A; RP3-423B22.1; zc3h12a; zc3h12a {ECO:0000312; Zinc finger CCCH domain-containing protein 12A; zinc finger CCCH type containing 12A; zinc finger CCCH-type containing 12A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 80149
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q5D1E8
Gene Symbols: ZC3H12A
Immunogen: KLH conjugated synthetic peptide between 331-358 amino acids from the central region of human ZC12A
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZC3H12A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZC3H12A
Gene Alias:
BC036563; bifunctional endoribonuclease and deubiquitinase ZC3H12A; dJ423B22.1; Endoribonuclease ZC3H12A; MCP-1 treatment-induced protein; MCP-induced protein 1; MCPIP; MCPIP1; Monocyte chemotactic protein-induced protein 1; Reg1; Regnase-1; RGD:1306776}; RGD1306776; ribonuclease ZC3H12A; RP3-423B22.1; zc3h12a; zc3h12a {ECO:0000312; Zinc finger CCCH domain-containing protein 12A; zinc finger CCCH type containing 12A; zinc finger CCCH-type containing 12A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
80149
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q5D1E8
Gene Symbols:
ZC3H12A
Immunogen:
KLH conjugated synthetic peptide between 331-358 amino acids from the central region of human ZC12A
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DMP4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FAM20C
Gene Alias: C76981; Dentin matrix protein 4; DMP4; DMP-4; Extracellular serine/threonine protein kinase FAM20C; Fam20c; family with sequence similarity 20 member C; family with sequence similarity 20, member C; GEF-CK; Golgi casein kinase; golgi-enriched fraction casein kinase; Kiaa4081; mKIAA4081; RGD1311980; RNS
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56975
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q8IXL6
Gene Symbols: FAM20C
Immunogen: KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human DMP4
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DMP4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FAM20C
Gene Alias:
C76981; Dentin matrix protein 4; DMP4; DMP-4; Extracellular serine/threonine protein kinase FAM20C; Fam20c; family with sequence similarity 20 member C; family with sequence similarity 20, member C; GEF-CK; Golgi casein kinase; golgi-enriched fraction casein kinase; Kiaa4081; mKIAA4081; RGD1311980; RNS
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56975
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q8IXL6
Gene Symbols:
FAM20C
Immunogen:
KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human DMP4
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BCLAF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BCLAF1
Gene Alias: 2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9774
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9NYF8
Gene Symbols: BCLAF1
Immunogen: KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BCLAF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BCLAF1
Gene Alias:
2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9774
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9NYF8
Gene Symbols:
BCLAF1
Immunogen:
KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG