PIPA524963
GRP78 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA524963-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA524963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
GRP78
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hspa5
Gene Alias
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) membe
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3309, 378848
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P11021
Gene Symbols
Hspa5
Immunogen
KLH conjugated synthetic peptide between 261-289 amino acids from the central region of human HSPA5
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Zebrafish
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology
- GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
- GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
- GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
- The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
- The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
- GRP78’s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
- GRP78 is critical for maintenance of cell homeostasis and the prevention of apoptosis
- GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
- GRP78 levels are reduced in the brains of Alzheimer's Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
- Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.
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Antigen: GRP78
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hspa5
Gene Alias: 78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) membe
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3309, 378848
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P11021
Gene Symbols: Hspa5
Immunogen: KLH conjugated synthetic peptide between 261-289 amino acids from the central region of human HSPA5
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
GRP78
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hspa5
Gene Alias:
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) membe
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3309, 378848
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P11021
Gene Symbols:
Hspa5
Immunogen:
KLH conjugated synthetic peptide between 261-289 amino acids from the central region of human HSPA5
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: HVCN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HVCN1
Gene Alias: 0610039P13Rik; AI450555; BTS; HV1; Hvcn1; hydrogen voltage gated channel 1; hydrogen voltage-gated channel 1; mVSOP; RGD1310788; UNQ578/PRO1140; Voltage sensor domain-only protein; voltage-gated hydrogen channel 1; Vsop; Vsop.
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 84329
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q96D96
Gene Symbols: HVCN1
Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HVCN1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HVCN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HVCN1
Gene Alias:
0610039P13Rik; AI450555; BTS; HV1; Hvcn1; hydrogen voltage gated channel 1; hydrogen voltage-gated channel 1; mVSOP; RGD1310788; UNQ578/PRO1140; Voltage sensor domain-only protein; voltage-gated hydrogen channel 1; Vsop; Vsop.
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
84329
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q96D96
Gene Symbols:
HVCN1
Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HVCN1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ISM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ISM1
Gene Alias: 5430433G21Rik; bA149I18.1; C20orf82; dJ1077I2.1; ISM; ISM1; Isthmin; isthmin 1 homolog; isthmin 1 homolog (zebrafish); isthmin 1, angiogenesis inhibitor; isthmin-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 140862
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: B1AKI9
Gene Symbols: ISM1
Immunogen: KLH conjugated synthetic peptide between 435-464 amino acids from the C-terminal region of human ISM1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ISM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ISM1
Gene Alias:
5430433G21Rik; bA149I18.1; C20orf82; dJ1077I2.1; ISM; ISM1; Isthmin; isthmin 1 homolog; isthmin 1 homolog (zebrafish); isthmin 1, angiogenesis inhibitor; isthmin-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
140862
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
B1AKI9
Gene Symbols:
ISM1
Immunogen:
KLH conjugated synthetic peptide between 435-464 amino acids from the C-terminal region of human ISM1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MAGT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Magt1
Gene Alias: 2410001C15Rik; 2610529C04Rik; 2810482I07Rik; bA217H1.1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1; Iag2; IAP; Implantation-associated protein; magnesium transporter 1; magnesium transporter protein 1; MAGT1; MRX95; Oligosaccharyl transferase subunit MAGT1; oligosaccharyltransferase 3 homolog B; OST3B; PRO0756; PSEC0084; UNQ628/PRO1244; XMEN
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 67075, 84061
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9CQY5, Q9H0U3
Gene Symbols: Magt1
Immunogen: KLH conjugated synthetic peptide between 44-71 amino acids from the N-terminal region of human MAGT1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MAGT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Magt1
Gene Alias:
2410001C15Rik; 2610529C04Rik; 2810482I07Rik; bA217H1.1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1; Iag2; IAP; Implantation-associated protein; magnesium transporter 1; magnesium transporter protein 1; MAGT1; MRX95; Oligosaccharyl transferase subunit MAGT1; oligosaccharyltransferase 3 homolog B; OST3B; PRO0756; PSEC0084; UNQ628/PRO1244; XMEN
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
67075, 84061
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9CQY5, Q9H0U3
Gene Symbols:
Magt1
Immunogen:
KLH conjugated synthetic peptide between 44-71 amino acids from the N-terminal region of human MAGT1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG